Protein Alignment Ugt36E1 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_609911.1
• Gene: Ugt36E1 / 35139
• FlyBaseID: FBgn0027070
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 138/513 - (26%)
• Similarity: 249/513 - (48%)
• Gaps: 53/513 - (10%)

  Fly    35 SHFKFFHPIMRGLAEAGHSVDVI----SPFEDKDPPNGYKDHLLPPSTLTDTISLEDFE------ 89
            ||:.....|::.|.:.||.|.|:    |...|.:..:..|..:.|.| ||.|    :||
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTS-LTKT----EFENIIMQQ 93

  Fly    90 -------RPYSFLFHYVE----FFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILLEQFNTD 143
                   |..||..::.:    .:.|:.:.|..|...:.::.:.:.|:.  ..:|::..:.. ..
Human    94 VKRWSDIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQE--SRFDIVFADAV-FP 155

  Fly   144 CAMSVAHVFQAPVIGMSSCALMP-WHYERFGAPLI--PSYISALFQGQSQEMSFAGRLGNWITVH 205
            |...:|.:.....:  .|....| :..||....||  ||||..:....|.:|:|..|:.|.|.|.
Human   156 CGELLAALLNIRFV--YSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVL 218

  Fly   206 SLNLLYKMFTVPAGNALIRQRFGPGLPST-EDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVH 269
            ..:..::|..:...:....:..  |.|:| .:.:....:.|:...:|...|.|..|||..|||.|
Human   219 YFDFWFQMSDMKKWDQFYSEVL--GRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFH 281

  Fly   270 ISPPKPLPSDLQKILDNA-PKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTL 333
            ..|.||||.::::.:.:: ..||::.|.||.:.  :::|.|.:.|..|:.::.|:|:|:::.
Human   282 CKPAKPLPKEMEEFVQSSGENGVVVFSLGSVIS--NMTAERANVIATALAKIPQKVLWRFDG--- 341

  Fly   334 PNKPP----NLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAA 394
             |||.    |..:.||:||.|:|.||..:.|::|||..|..||:...:|:||:|::.||..|||.
Human   342 -NKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAH 405

  Fly   395 LVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAET 458
            :..:|.|::|:...:....:..||...: ||.:|....:::...:::...||:.|::|:|.|...
Human   406 MKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPH 470

  Fly   459 KGAPLTQPSAVHLSRFVYYSLDV--YSVVALSLLLPVITLLGLIRMFK--RREPKGDR 512
            |||...:.:|..|:.|.|:||||  :.:..::.::.:||...|...:|  |:..||.|
Human   471 KGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFARKGKKGKR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	119/455 (26%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	135/508 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150140
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.740