DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36E1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	542	Identity:	156/542 - (28%)
Similarity:	257/542 - (47%)	Gaps:	79/542 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFCLLALLSLVAFSDSL-----RILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPP 66
            |..::.::.:|..|.:|     :|| :|||.. ||:...:.::..|...||.:.||...:....|
Zfish    31 VMDIIFVVQIVVLSLTLPVHCGKIL-VFPHEG-SHWLNLNTLIEELHHRGHQISVIRALDSWYIP 93

  Fly    67 NGYKDHLLPPSTLTDTISLE-----DFERPYSFLFHYVEF--------FIL--------HKMGRE 110
            .        .|...|:|::.     |.:..:||:|..::.        |.|        .:|.|:
Zfish    94 E--------TSPHYDSINVPFLLGGDDQFYHSFIFRQLQIRREQRWTRFKLDMELKEKFSEMHRK 150

  Fly   111 DCNTTLHSRALTEILKNPPGY--------YDVILLEQFNTDCAMSVAHVFQAPVI--------GM 159
            .|...:|      |::..|..        :|::|.:..|.. .:.:||....|::        |.
Zfish   151 ICEMVIH------IVEKEPAIMKQIKEANFDIMLTDPANGG-GVVLAHYLHLPLVFNVQWTVHGE 208

  Fly   160 SSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIR 224
            :..|:         ||..|||:.......:..|||..|:.|.:.......||:....|..:||..
Zfish   209 AHFAI---------APSPPSYVPFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALCN 264

  Fly   225 QRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPK 289
            :.|||||...| |.:...:.|:...|....|:|..||||.:||.|.||.|.||.||:..|.::.:
Zfish   265 RLFGPGLDYFE-LFQAADIWLMRADFVFDFPRPTMPNVIYIGGFHCSPAKALPKDLEDFLQSSGE 328

  Fly   290 -GVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILA 353
             |||::|.|:.:....:..|  |.||.|...|.|:|||:|..|...|...|..:..||||.|:|.
Zfish   329 HGVIVMSLGTLVAQLPMDIA--DEIVAAFAELPQKVIWRYTGDRPANVGNNTLLVNWLPQNDLLG 391

  Fly   354 HPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEAL 418
            ||..:||:||||..|..||:...|||||:|:..||..|:..:..:|:|..|::..::.|...:||
Zfish   392 HPKTRVFVSHGGTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDAL 456

  Fly   419 TKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVY 482
            .:.| |||:::..::::|.:.:....||::|::|.|.|...:||...:..:..:..:.|:|:||
Zfish   457 QEVLNDPSYRSNMQKLSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVDV- 520

  Fly   483 SVVALSLLLPVITLLGLIRMFK 504
            .|..:|:|..::.|     |||
Zfish   521 GVFLVSVLCFIVFL-----MFK 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	143/496 (29%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740