DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt5d1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001170967.1	Gene:	ugt5d1 / 100415794	ZFINID:	ZDB-GENE-091118-36	Length:	532	Species:	Danio rerio

Alignment Length:	558	Identity:	157/558 - (28%)
Similarity:	266/558 - (47%)	Gaps:	101/558 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSLVAFSDSL---RILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISP-----FEDKDPPNGYK 70
            |:|.||:.|.   :|| |:|... ||:.....::..|...|||:.||.|     ..:|.|
Zfish    16 LALSAFTLSCSGGKIL-LYPVDG-SHWVNMKVLIEELHSRGHSITVIRPKSSWYITEKSP----- 73

  Fly    71 DHLLPPSTLTDTIS-LEDFERPY---------------SFL-FHYVEFFIL---HKMGREDCNTT 115
              |....|:.|.:: .|:|...|               :|| ..|..|.:|   |::..:..:..
Zfish    74 --LYTSITIQDNVNDFENFFEDYLSKAMEIERGEGSGLAFLKLQYDLFSMLSTAHEIACKMVSII 136

  Fly   116 LHSRALTEILKNPPGYYDVILLEQFNTDCAMS----VAHVFQAPVI--------GMSSCALMPWH 168
            |..:.|.:.|::.  .||::|     ||.|::    :||..:.|::        |....|:.|
Zfish   137 LEDKMLVKKLQDE--QYDLML-----TDPAIAGGVFLAHYLKLPLVLNVRWITSGEGHFAIAP-- 192

  Fly   169 YERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRF--GPGL 231
                 :|:  |||.....|.:.:|.||.|:        .|:|:|.||      .::.||  ||..
Zfish   193 -----SPM--SYIPLPGSGHTDKMGFAQRV--------KNVLFKTFT------FLQNRFVVGPHY 236

  Fly   232 PSTED-----------LVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILD 285
            ....|           |::...:.|:...|....|:|..||::.:||....|.||||:||:....
Zfish   237 DILIDKYLDYKTDIVGLIQAADIWLMRADFVFEFPRPTMPNIVYMGGFRCKPSKPLPADLEAFAQ 301

  Fly   286 NAPK-GVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQR 349
            ::.: |.|::|.|:.:|  ||.|...:.|..|..||.|:|||::..|...|...|..|..|:||.
Zfish   302 SSGEHGFIIMSLGTLVK--SLPADMANAIAAAFARLPQKVIWRHLGDRPSNVGNNTLIVDWMPQN 364

  Fly   350 DILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTV 414
            |:|.|..:|.|::|||..|..||:...||::|||::.||..|:..:..:|....|:|.:|:....
Zfish   365 DLLGHSKIKAFVAHGGTNGVQEAIFHGVPVLGVPLFFDQFDNLIRVQGKGAGKILKLSELNAEAF 429

  Fly   415 YEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYS 478
            .:||.::| |.|:|...:.:::.:.::...||:|||:|:|||...|||...:.....:..:.|:|
Zfish   430 EQALRESLNDGSYKRNMQTLSTLHRDQPMRPLDTAIFWIEHVIRHKGATHLRSEFYKMPWYSYHS 494

  Fly   479 LDVYSVVALSLLLPVITLLGLIR--MFK---RREPKGD 511
            :||:.|:.:...:.:::.:.:||  .:|   ||:.|.:
Zfish   495 VDVFLVLFIVAAVCMLSTIAVIRYVCYKICCRRKSKSE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	143/500 (29%)
ugt5d1	NP_001170967.1	UDPGT	28..527	CDD:278624	149/539 (28%)
ugt5d1	NP_001170967.1	egt	<267..506	CDD:223071	82/240 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584396
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740