DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt5c1

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001170966.1	Gene:	ugt5c1 / 100415793	ZFINID:	ZDB-GENE-050419-68	Length:	531	Species:	Danio rerio

Alignment Length:	539	Identity:	150/539 - (27%)
Similarity:	251/539 - (46%)	Gaps:	72/539 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLSLVAFSDSLRILGLFPHPAI-------------SHFKFFHPIMRGLAEAGHSVDVI---SP 59
            :|.||...||.||.|..:....::             ||:.....:::.|...||:||||   :.
Zfish     1 MAQLSKNTFSVSLWITVMIIFGSLCDGGKILVAPLEGSHWVNMDILIKALHGQGHTVDVIRNTNS 65

  Fly    60 FEDKDPPNGYKDHLLPPSTLTDTISLE-------DFERPYSFLFHYVEFFI--------LHKMGR 109
            :..|:....|....:|.|...|...:|       |:||........|:.|:        .||:..
Zfish    66 WFVKENSTYYNSITIPDSKGMDEEFVEDVLTKKIDYERGKGSWLGGVQLFLDVSKAVYESHKLVC 130

  Fly   110 EDCNTTLHSRALTEILKNPPGYYDVILLEQFNTD----CAMSVAHVFQAPVIGMSSCALMPW--- 167
            ........|..:.:.|:...  ||::|     ||    ..:.:||..:.|::     ..:.|
Zfish   131 RLITNIFESEDILKALQEKK--YDLML-----TDPGWGTGIILAHKLKLPMV-----YNVRWTTP 183

  Fly   168 ---HYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGP 229
               |::...:|:  |||.....|.:.:|||..|:.|......|:.....|.||...||..:.|.|
Zfish   184 GEGHFDIAPSPM--SYIPLTGSGNTDKMSFFQRVINVFYYLLLDFQCSRFNVPQYQALCDKYFDP 246

  Fly   230 GLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNA-PKGVIL 293
            .:...: |::...|.|:...|....|:|..||:|..||...:|.||||.||:..:.:: ..|||:
Zfish   247 PVDFYK-LLQGADLWLMRVDFVFEFPRPTMPNIIYTGGFQCTPTKPLPHDLEDFMQSSGDHGVIV 310

  Fly   294 ISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKY---ENDTLPNKPPNLHIRKWLPQRDILAHP 355
            :|.||.:..  |.......|..|..||.|:|||:|   :..||.|   |..:..|:||:|:|.||
Zfish   311 MSLGSFISV--LPDYVSSEIAAAFARLPQKVIWRYTGKKPSTLGN---NTLLVDWMPQKDLLGHP 370

  Fly   356 NLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTK 420
            ..|:|::|||..|..||:...||::|:|.:.||..|:..|..||.|..:.|.:|.||:::.|:.:
Zfish   371 KTKLFIAHGGTNGVQEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIQE 435

  Fly   421 AL-DPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSV 484
            .: :||::...::::..:.::...||::||:|:|.|...|||...:..:..:..:.|:|:||
Zfish   436 VINEPSYRLNMQKLSYLHRDKPVEPLDSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDV--- 497

  Fly   485 VALSLLLPVITLLGLIRMF 503
               |:.|..:.|:.:..||
Zfish   498 ---SVTLIAVVLIFIYSMF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	138/494 (28%)
ugt5c1	NP_001170966.1	UDPGT	28..530	CDD:278624	142/512 (28%)
ugt5c1	NP_001170966.1	egt	<267..507	CDD:223071	83/250 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.740