DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36E1 and ugt2a3

DIOPT Version :9

Sequence 1:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001170814.2	Gene:	ugt2a3 / 100384900	ZFINID:	ZDB-GENE-080721-22	Length:	532	Species:	Danio rerio

Alignment Length:	523	Identity:	141/523 - (26%)
Similarity:	256/523 - (48%)	Gaps:	66/523 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKD----HLLPPSTLTDTISLEDFERPYS-F 94
            ||:.....|:..|.:..|||.|:........|:..|.    |:...:     |..|:.:..:| |
Zfish    31 SHWHNMRAIIEALVDRNHSVTVLVGSSSPTVPHTQKARFDYHVFKVN-----IEKEEADAVWSDF 90

  Fly    95 LFHYVE------------FFILHK-----------MGREDCNTTLHSRALTEILKNPPGYYDVIL 136
            ::.::.            |.::.:           |.:||         |.::|:.  .:|||:.
Zfish    91 IYLWMNETATKYETVSNIFQVMSRFMTLTDEVCKGMFKED---------LLQMLRE--SHYDVLF 144

  Fly   137 LEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERF--GAPLIPSYISA--LFQGQSQEMSFAGR 197
            .:.. ..|:..:|.....|:: :|..|...:.:||.  ..|..|||:.|  |....:..|||..|
Zfish   145 SDPM-MPCSDLMAQTLNIPLV-LSLRATFAYSFERMCGQMPAPPSYVPAASLRDHLTDRMSFMER 207

  Fly   198 LGNWITVHSLNL---LYKMFTVPAGNALIRQRFGPGLPSTE-DLVRNTSLMLVNQHFSLSGPKPL 258
            :.|.:...|.::   ||.|||.......||     |.|:|. :.:....:.|:..::....|:|.
Zfish   208 VENMLLYFSHDVFFKLYMMFTFDRIYTEIR-----GKPTTMCETMGKADIWLIRTYWDFEYPRPF 267

  Fly   259 PPNVIEVGGVHISPPKPLPSDLQKILDNA-PKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQ 322
            |||...|||:|..|.|||..::::.:.:: ..||::.|.||.:|  :|::.|.:.|..|:|::.|
Zfish   268 PPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIAAALGQIPQ 330

  Fly   323 EVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGD 387
            :|:|:|...|.....||..|..|:||.|:|.||..|.|::|||..|..||:...||:||:|::.|
Zfish   331 KVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFAD 395

  Fly   388 QSLNIAALVQRGMALQLELKKLDENTVYEALTKAL-DPSFKARAKEVASSYNNRIQGPLETAIWW 451
            |..|:..:..:|.|:.|::..|:...:.:||...| :||:|.....::..::::...||:.|::|
Zfish   396 QPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYW 460

  Fly   452 VEHVAETKGAPLTQPSAVHLSRFVYYSLDVYS-VVALSLLLPVITLLGLIRMFKR--REPKGDRK 513
            :|.|...|||...:..|..||.:.|:.|||.: :::::.|:..:.:.....:|:|  |:.:.:||
Zfish   461 IEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERK 525

  Fly   514 LKR 516
            .::
Zfish   526 TQK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	125/462 (27%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	138/512 (27%)
		REC	<129..>178	CDD:302758	13/61 (21%)
		egt	<254..485	CDD:223071	78/232 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584374
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930