Protein Alignment Ugt36D1 and UGT8

DIOPT Version :9

• Sequence 1: NP_001246082.2
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 146/512 - (28%)
• Similarity: 256/512 - (50%)
• Gaps: 32/512 - (6%)

  Fly     2 WSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAG-HDVSVVSHF 65
            ::|...||:.|:.::      :||   |::.:.|....||.:.|..:...|.|.| |.|.::|..
Human     4 YTPYFILLWSAVGIA------KAA---KIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEG 59

  Fly    66 PDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYS---HFQEFFLLYDWGKQTCNLTLRSEALQ 127
            .|..|..||......|:...|.|......:.|..:|   ...|.|.:.|...:.|:|.:.:.||.
Human    60 RDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVGNHALI 124

  Fly   128 QILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQ 192
            |.|::. :||:::::. |..|...:||.|.......|:.:   |:...:|||...:::|......
Human   125 QGLKKE-KFDLLLVDP-NDMCGFVIAHLLGVKYAVFSTGL---WYPAEVGAPAPLAYVPEFNSLL 184

  Fly   193 SQHMNFGGRLANWFSTHALNWM-YKLLSVPAADAMVQ-YKFGHDVP--SVGELVKNTSMFFVNQH 253
            :..||...|:.| ...:.::.: ...|.:|..:.::| |..   :|  |:.:||..:|::.:...
Human   185 TDRMNLLQRMKN-TGVYLISRLGVSFLVLPKYERIMQKYNL---LPEKSMYDLVHGSSLWMLCTD 245

  Fly   254 YSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGI 317
            .:|..|:.|.|||:.:|||..:.:.|||.||||.::.| |.|.:|:|:|:.::..|...|.:  :
Human   246 VALEFPRPTLPNVVYVGGILTKPASPLPEDLQRWVNGANEHGFVLVSFGAGVKYLSEDIANK--L 308

  Fly   318 IRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVP 382
            ..|:.||.|||||::......|...|..:::||||.|:|.|..:|.|:|||||....|..|.|||
Human   309 AGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVP 373

  Fly   383 VVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQ 446
            ||..|::||.:.....:..:|||.:|.::.:.|..:..||.|.::. .:...|:.:|.....:|.
Human   374 VVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPG 438

  Fly   447 QALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLAL--VLGSIIASWV 501
            ..::..|:|::::....||..|:.:..::|...|:.||:..||.|  .|...:.|||
Human   439 HPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	133/470 (28%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	141/489 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740