Protein Alignment Ugt36D1 and UGT2B10

DIOPT Version :10

• Sequence 1: NP_609910.1
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001066.1
• Gene: UGT2B10 / 7365
• HGNCID: 12544
• Length: 528
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 128/503 - (25%)
• Similarity: 245/503 - (48%)
• Gaps: 46/503 - (9%)

  Fly    48 IMKGLAEAGHDVSVVSHF------PDKHPVAHYKDFPLTGMDK--LTNSV-----DLKFFEKRTF 99
            |:|.|.:.||:|:|::..      |:.......:.:| |.:.|  ..|.:     .|...:|.||
Human    41 ILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYP-TSLTKTEFENIIMQLVKRLSEIQKDTF 104

  Fly   100 YSHF-QEFFLLY---DWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPV 160
            :..| ||..:|:   |..:..|...:.::.|.:.|:. .|||::..:.: ..|...:|.....|.
Human   105 WLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQE-SRFDIVFADAY-LPCGELLAELFNIPF 167

  Fly   161 IALSSCVMMPWHYERMGAPLI--PSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAA 223
            : .|......:.:||.....|  ||::|.:....|..|.|..|:.|.......::.:::.::...
Human   168 V-YSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKW 231

  Fly   224 DAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRIL 288
            |.......|... ::.|.::...::.:...::...|....|||..:||:|.:.:||||.:::..:
Human   232 DQFYSEVLGRPT-TLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFV 295

  Fly   289 DNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPP----NMHIMK 348
            .:: |.||::.|.|||:  ::::..:.:.|..|:|::.|||:|:::.    |:|.    |..:.|
Human   296 QSSGENGVVVFSLGSMV--SNMTEERANVIATALAKIPQKVLWRFDG----NKPDALGLNTRLYK 354

  Fly   349 WLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDI 413
            |:||.|:|.||..:.|::|||..|..||.|.|:|:|..|::.||..|.|.:..:|....::|..:
Human   355 WIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTM 419

  Fly   414 GENTVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSR 477
            ....::.|||..: |..:.:....:|...|.:|.:.|..|::|:|.|....||..|:.:|..::.
Human   420 SSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTW 484

  Fly   478 FVYYSLDVYAVLALVLGSIIASWVWLLRLCC------GSSAAQKTKKD 519
            |.|:||||...|.    :.:|:.::::..||      .:...:|.|:|
Human   485 FQYHSLDVIGFLL----ACVATVLFIITKCCLFCFWKFARKGKKGKRD 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_609910.1	GT1_Gtf-like	28..457	CDD:340817	109/433 (25%)
UGT2B10	NP_001066.1	UDPGT	23..524	CDD:278624	125/497 (25%)