Protein Alignment Ugt36D1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_609910.1
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 566
• Identity: 149/566 - (26%)
• Similarity: 249/566 - (43%)
• Gaps: 104/566 - (18%)

  Fly     5 RVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVV------- 62
            ||.|| ||..|:|       ||.|.|:   |..| ||:.....|::.|:..||:|.||
Mouse    13 RVCLL-LAFGLAQ-------AGRLLVV---PMDG-SHWFSMKMIVEKLSHRGHEVVVVIPEVSWH 65

  Fly    63 ----SHFPDK--------HPVAHYKDF--------PLTGMDKLTNSVDLKFFEKRTFYSHFQEFF 107
                .:|..|        ..::|:.:|        ...||..|.......||:  ..:||
Mouse    66 LGKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQ--VLFSH----- 123

  Fly   108 LLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWH 172
                     |......:.|.:.|::.. ||.:.::.|:. |.:.:|.....|.:..|..:..  |
Mouse   124 ---------CRSLFNDKKLVEYLKQRS-FDAVFLDPFDV-CGLTIAKYFSLPSVVFSGGIFC--H 175

  Fly   173 YERMGA--PLIPSHIPALFMAQSQHMNFGGRLANWFS------------THALNWMYKLLSVPAA 223
            |...||  |..||::|.:....:..|.|..|:.|:||            ..|:....::|..|.
Mouse   176 YLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQTPV- 239

  Fly   224 DAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRIL 288
                         ::.:|..:.|::.....:.|..|:...||::.:|||:....|||..:.:..:
Mouse   240 -------------TMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYV 291

  Fly   289 D-NAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQ 352
            : :.|.|:::.|.|||:  :.:...|...|..|:.|:.|.|:|::......|...|..::|||||
Mouse   292 NASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQ 354

  Fly   353 RDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENT 417
            .|:|.||..:.|::|.|..|..|....|||:|..|::|||..|...:..||.|..||..::..:.
Mouse   355 NDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 419

  Fly   418 VMRALKKALDKKFHDAAKVVSHSFH-HRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYY 481
            :..|||..::.|.:....:...|.| .||.:.|..|::|||:|....|||.|:|:|.:::.:.|:
Mouse   420 LENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYH 484

  Fly   482 SLDVYAVLALVLGSIIASWVWLLRLCC---------GSSAAQKTKK 518
            ||||...|.    :|:.:.|:::..||         |....:|:.|
Mouse   485 SLDVIGFLL----AIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_609910.1	GT1_Gtf-like	28..457	CDD:340817	117/471 (25%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	138/538 (26%)