DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	542	Identity:	150/542 - (27%)
Similarity:	245/542 - (45%)	Gaps:	91/542 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VALLFL--ALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVV----SH 64
            ::|:||  :|.||.|    ......|:| :||..| ||:.....::|.|...||::||:    |.
Zfish     5 MSLVFLWTSLLLSLP----SGYNADKIL-VFPIDG-SHWVNMEVLVKKLQSRGHELSVIRLEDSW 63

  Fly    65 FPDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRT--------------FYSHFQEFFLLYDWGKQ 115
            | .|....:|....:|...|.   :||..||...              ..:...||..:...| .
Zfish    64 F-IKGNSPYYSSITVTLKKKF---IDLDLFETAVKKILDARRDGPIMGVLAQMSEFIGILKVG-H 123

  Fly   116 TCNLTLRSEALQQILRRPGRFDVIIMEQF---NTDCMM-------GV--AHQLQAPVIALSSCVM 168
            ..|:.:.:..|:         :.::|.|.   |.|.|:       ||  ||.|..|::     ..
Zfish   124 GANIAMLTSMLE---------NKVLMSQIKMANYDLMLTDPAMPGGVILAHYLHLPMV-----YN 174

  Fly   169 MPW------HYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALN-----WMYKLLSVPA 222
            :.|      |:....:|:  |.:|......:..|....|..| |..:.||     ||.    :|.
Zfish   175 VRWMSFGEGHFSIAPSPI--SFVPVPGSGLTDRMGLLERSRN-FLHYGLNLIQERWMV----IPM 232

  Fly   223 ADAMVQYKF--GHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQ 285
            ..:::...|  |.|:.:   :.::..::.|...:....|:.:.||::.:||...:.:|||||||:
Zfish   233 YTSLLLNHFPPGTDLLT---MQRSAELWLVRADFVFEFPRPSMPNLVYIGGFQCRPAKPLPADLE 294

  Fly   286 RILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENE---TLPNQPPNMHI 346
            ..:.:: :.||:::|.|::|.  .|.....:.|..|.|::.|||||::..:   ||.|   |..:
Zfish   295 EFMQSSGDHGVVVMSLGTLIA--GLPKEVMEAIASAFAQIPQKVIWRFIGQRPSTLGN---NTLL 354

  Fly   347 MKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFE 411
            ::||||.|:|.||..:.|::|||..|..||.|.||||:..|:..||..|...|..||...:|:..
Zfish   355 IQWLPQNDLLGHPKTRAFVAHGGTNGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAA 419

  Fly   412 DIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEM 475
            .......:.||...|:. .:....:.:|:....||...|..|::|:|.|....|||.|:..|..:
Zfish   420 TCSTKEFLVALTDILENPTYRQNMQKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNV 484

  Fly   476 SRFVYYSLDVYA-VLALVLGSI 496
            |.|.||.|||.| ||.::||::
Zfish   485 SEFSYYCLDVVALVLFMLLGTL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	134/508 (26%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	150/542 (28%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	143/518 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740