Protein Alignment Ugt36D1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_001246082.2
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 135/508 - (26%)
• Similarity: 250/508 - (49%)
• Gaps: 45/508 - (8%)

  Fly    40 SHFHFFHPIMKGLAEAGHDVSVVSHFP--------------DKHPVAHYK-DFPLTGMDKLTNSV 89
            ||:.....|:|.|.:.||:|:|::...              :.:|.:..| :|....|.::....
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWS 98

  Fly    90 DLKFFEKRTFYSHF-QEFFLLYDWG---KQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMM 150
            |:   :|.:|:.:| ||..:|:::.   :..|...:.::.:.:.|:. .|||:|..:.| ..|..
Human    99 DI---QKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQE-SRFDIIFADAF-FPCGE 158

  Fly   151 GVAHQLQAPVIALSSCVMMPWHYERMGAPLI--PSHIPALFMAQSQHMNFGGRLANWFSTHALNW 213
            .:|..|..|.: .|.|....:..||....||  ||:||.:....|..|.|..|:.|.......::
Human   159 LLAALLNIPFV-YSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDF 222

  Fly   214 MYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSK 278
            .:::..:...|.......|... ::.|.:....::.:...:|...|....||:..:||:|.:.:|
Human   223 WFQMCDMKKWDQFYSEVLGRPT-TLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAK 286

  Fly   279 PLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPP 342
            |||.:::..:.:: |.||::.|.||:|  ::::|.:.:.|..|:|::.|||:|:::.    |:|.
Human   287 PLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIPQKVLWRFDG----NKPD 345

  Fly   343 ----NMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERG 403
                |..:.||:||.|:|..|..:.|::|||..|..||.|.|:|:|..|::.||..|.|.:..:|
Human   346 ALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKG 410

  Fly   404 MGTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPL 467
            ....|:|..:....::.|||..: |..:.:....:|...|.:|.:.||.|::|:|.|....||..
Human   411 AAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKH 475

  Fly   468 LKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLC--CGSSAAQKTKK 518
            |:.:|.:::.|.|:||||...|...:.::|   ..:.:.|  |....|:|.||
Human   476 LRVAARDLTWFQYHSLDVIGFLLACVATVI---FVVTKFCLFCFWKFARKGKK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	123/468 (26%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	133/506 (26%)
		egt	<269..506	CDD:223071	78/245 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150138
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740