DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and Ugt302K1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	156/497 - (31%)
Similarity:	258/497 - (51%)	Gaps:	28/497 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSH 102
            |.|||:..|.:.|||.:|||.::|||.||.|.|:..|.|.      .:.|.:::...:....::.
  Fly    30 GRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDV------SVPNVIEVMGGDIGALWAS 88

  Fly   103 FQEFFLL-----YDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIA 162
            .|:.:..     |..|.:...........|..|:....||.||.|.|..|...|:|....||:|.
  Fly    89 IQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIG 153

  Fly   163 LSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLS---VPAAD 224
            |::...:.:..:.:|:|...|.:|.:.:..:.||:...||.|   ...|.:...||.   :|..:
  Fly   154 LATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLN---VAFLGYERVLLDYYFLPTQE 215

  Fly   225 AMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ-KSKPLPADLQRIL 288
            .:.:..|..:.....::.:|.|:..:|||.|||.|:...||:||:||:||. |..|||..::|.:
  Fly   216 KLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFI 280

  Fly   289 DNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQR 353
            :.:|.|.|..|.||.::...|..:|...|::|:..|||:|:||:|.:.|||:|.|::|..|.||.
  Fly   281 NESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQT 345

  Fly   354 DILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTV 418
            |||.||.:..|::|||::.|:|:.|...||:..|::.|||.|.|...:.|.|.:|:|:.:.....
  Fly   346 DILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEF 410

  Fly   419 MRALKKALDKKFHDAAKVVSH-SFHHRPQQ--ALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVY 480
            .:|:::...:..:  .|||.. ||.:|.||  .:..||:|||||....||..||.:|..::.:.|
  Fly   411 RKAIERITSEPSY--TKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQY 473

  Fly   481 YSLDVYAVLALVLGSI-----IASWVWLLRLCCGSSAAQKTK 517
            :::||..::.:|:..:     |..:..|.:|.......|.||
  Fly   474 HNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	147/455 (32%)
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	149/460 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454602
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890