DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and RGD1559459

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_003751392.1	Gene:	RGD1559459 / 501907	RGDID:	1559459	Length:	530	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	137/512 - (26%)
Similarity:	248/512 - (48%)	Gaps:	47/512 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SHFHFFHPIMKGLAEAGHDVSVV------SHFPDKHPVAHYKDFP---------LTGMDKLTNSV 89
            ||:.....|:..|.:.||:|.|:      |:..||.....::.||         :..||.:..|:
  Rat    34 SHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMDCVNESI 98

  Fly    90 DLKFFE--KRTFYSHFQEFFLLY----DWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDC 148
                :|  |::|:.:|.....|:    |:.::.|.....::.|...|:..| ||||:.:.| |.|
  Rat    99 ----YELPKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSG-FDVILADPF-TPC 157

  Fly   149 MMGVAHQLQAPVIALSSCVMMPWH-YERM--GAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHA 210
            ...:|..|:.|::  .|....|.. ||:.  |.|:.||::|......|..|.|..|:.:......
  Rat   158 GDLLAEILKIPLV--YSLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVERVKHMIYVLC 220

  Fly   211 LNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ 275
            .::.:::......:.:.....|... ::.|.:....::.:..::.|..|....||...:||:|.:
  Rat   221 FDFWFQVFDEKKWNELYTEVLGRPT-TLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCR 284

  Fly   276 KSKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPN 339
            .:||||.:::..:.:: |.||::.|.|||:  .||:..:.:.|...:|::.|||:|::|.:....
  Rat   285 PAKPLPKEIEDFVQSSGEHGVVVFSLGSMV--GSLTEERANVIAAGLAQIPQKVLWRFEGKKPET 347

  Fly   340 QPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGM 404
            ...|..:.||:||.|:|.||..:.|::|||..|..||.|.|:|||..|::|||..|...|..:|.
  Rat   348 LGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQKDNIVHLKTKGA 412

  Fly   405 GTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLL 468
            ...|:|..:....::.||:... |..:.:.|..:|...|.:|.:.|..|::|:|.|....||..|
  Rat   413 AVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHL 477

  Fly   469 KPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCC------GSSAAQKTKKD 519
            :.:..::|...|:||||...|.    :.:.:.:::|:.||      .:.|.:|.||:
  Rat   478 RVAGHDLSWVQYHSLDVIGFLL----ACVVTVMFILKKCCLFCCQKFTKAGRKKKKE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	125/467 (27%)
RGD1559459	XP_003751392.1	UDPGT	24..527	CDD:278624	134/507 (26%)
RGD1559459	XP_003751392.1	egt	<270..508	CDD:223071	77/243 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740