DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and Ugt36A1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	183/531 - (34%)
Similarity:	302/531 - (56%)	Gaps:	25/531 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHP 70
            |.::.|...|..|:.:  :||  .:|.::||.|.|||....||:..||..|||::|:|:.  |:|
  Fly     9 VLIIVLLGILGIPEPI--SAG--NILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYV--KNP 67

  Fly    71 VA----HYKDFPLT--GMDKLTNSVDL----KFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEA 125
            .|    :|::..::  |.|:.:.:::|    :....|:.....:|:..|::.|::||.....|..
  Fly    68 QAGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGH 132

  Fly   126 LQQILRRPGR--FDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPAL 188
            :::.:.|...  :|:::.|.||:||.:.:|..|..|:|.||:|.:||::|:|:..|..|:.|.:.
  Fly   133 IERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSE 197

  Fly   189 FMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVK-NTSMFFVNQ 252
            |:..:..:|:..||.|:.....|.::||..|..|.:.:|:...|.:| .|.|:.: .|:..|.||
  Fly   198 FVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEV-DVEEVARTQTAFIFGNQ 261

  Fly   253 HYSLSGPKVTPPNVIELGGIHIQK--SKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRD 315
            ||||.|.:......:|:||:||.|  .:.||.::...|:.:.||||.||||||:||:|:...|..
  Fly   262 HYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRASSIDEDKLS 326

  Fly   316 GIIRAVARLKQKVIWKWENETLPNQPPNMHI-MKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYC 379
            .|:..:.....|:|||||.:..|:...:..: :||.||..:||||.||:|.|||||:||:|:.:|
  Fly   327 AILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHC 391

  Fly   380 GVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHR 444
            |.|::.||:|||||:|..::..||||..|:::||....:.:||.:.....:...:..||..|:.|
  Fly   392 GKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNER 456

  Fly   445 PQQALHTAIWWVEHVAHTG--GAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLC 507
            .|..|.:|||.||||...|  .|.||:...:|::.|||:|||..|::.|.|..:|....:|.:..
  Fly   457 QQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRN 521

  Fly   508 CGSSAAQKTKK 518
            ....|.:|..|
  Fly   522 PSKLAHKKVGK 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	168/478 (35%)
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	164/472 (35%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	165/465 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471432
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100631at6960
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	8.000