DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and Ugt303B1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	148/517 - (28%)
Similarity:	249/517 - (48%)	Gaps:	34/517 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHF---P 66
            |...|.|:|.|....:..:||   .:||:||:..:|.|....|:::.||..||:|::::..   .
  Fly     4 RYCWLTLSLCLLLQHDRAQAA---NILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPN 65

  Fly    67 DKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILR 131
            |...|.|.:      :.:|...:      |....|.....|::..|.:..........|...||.
  Fly    66 DIEGVRHIR------VAQLNERI------KEMLESDQVLDFMINKWTESALTAKALFNASNDILS 118

  Fly   132 RPG----------RFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWH-YERMGAPLIPSHI 185
            .||          .||:||||..:.|.:.|:.....|.::.||| :.:.|| ||..|.|....:.
  Fly   119 DPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSS-IRINWHTYELAGNPAPSIYE 182

  Fly   186 PALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFV 250
            |...:..|...:...|:.||........:..|:..||...:.|..||:....:.||....|:..:
  Fly   183 PISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLI 247

  Fly   251 NQHYSLSGPKVTPPNVIELGGIHIQKSKPLPAD--LQRILDNAEEGVILISWGSMIRANSLSAAK 313
            |.|||:...:...||:||:||:|:.: .|.|:|  ||:.||.|:.|||..|.|:.|....|....
  Fly   248 NSHYSMGKVRANAPNIIEVGGLHLSE-PPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENI 311

  Fly   314 RDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAY 378
            ::.:::..|.|.:.:|||.|...:|::..|:::::..|||.||.||||::|:::|||:...||..
  Fly   312 QELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVD 376

  Fly   379 CGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSFH 442
            .|||::..||:.|||.|...:...||..:::...:.::|:...:|..| :..::..||.:|..|.
  Fly   377 SGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFK 441

  Fly   443 HRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLL 504
            .||...|.||:||.|:.........::.:..|:....||.:|.....:|..|.:.||.::|:
  Fly   442 DRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLV 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	136/477 (29%)
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	134/457 (29%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	135/477 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454595
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890