Protein Alignment Ugt36D1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_609910.1
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 558
• Identity: 150/558 - (26%)
• Similarity: 258/558 - (46%)
• Gaps: 73/558 - (13%)

  Fly     2 WSPRVALL--FLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVS- 63
            ||.|:.||  :|.|.:..|.  ...||.|.|   ||..| ||:.....:::.|.:.||:|.|::
Mouse     6 WSSRLLLLLPYLLLCVFGPS--ASHAGRLLV---FPMDG-SHWLSMLGVIQQLQQKGHEVVVIAP 64

  Fly    64 ----HFPD-------KHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLL-----YDW 112
                |..:       |.||...|:      :.....|:|    .||.::  |:.|||     |..
Mouse    65 EASIHIKEGSFYTLRKFPVPFQKE------NVTATLVEL----GRTAFN--QDSFLLRVVKIYMK 117

  Fly   113 GKQTCNLTL--------RSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMM 169
            .|:..::.|        .:|.:..:  ....||.::.:.| ..|...||..|..|.:...:.:..
Mouse   118 VKRDSSMLLAGCSHLLHNAEFMASL--EESHFDALLTDPF-LPCGSIVAQYLTVPTVYFLNKLPC 179

  Fly   170 PWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVP---AADAMVQYKF 231
            ....|....|:..|::|......|..|||..|:.|.....:.|:|.:::..|   .|..::|.:.
Mouse   180 SLDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEV 244

  Fly   232 GHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILD-NAEEGV 295
                 :|.:|:...|::.:...:....|:...||::.:|||:..:.|||..:.:..:: :.|.|:
Mouse   245 -----TVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASGEHGI 304

  Fly   296 ILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPN 360
            ::.|.|||:  :.:...|...|..|:.|:.|.|:|::......|...|..::|||||.|:|.||.
Mouse   305 VVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPK 367

  Fly   361 VKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKA 425
            .:.|::|.|..|..|....|||:|..|::|||..|...:..||.|..||..::..:.:..|||..
Mouse   368 TRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTV 432

  Fly   426 LDKKFHDAAKVVSHSFH-HRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVL 489
            ::.|.:....:...|.| .||.:.|..|::|||:|....|||.|:|:|.:::.:.|:||||...|
Mouse   433 INNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFL 497

  Fly   490 ALVLGSIIASWVWLLRLCC---------GSSAAQKTKK 518
            .    :|:.:.|:::..||         |....:|:.|
Mouse   498 L----AIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_609910.1	GT1_Gtf-like	28..457	CDD:340817	118/458 (26%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	139/525 (26%)