DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-39

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	121/540 - (22%)
Similarity:	215/540 - (39%)	Gaps:	103/540 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LFPHPGVSHFHFFHPIMKGLAEAGHDVSV-----------VSHFPDKHPVAHYKDFPLTGMDKLT 86
            ||.|   ||..||..|...|.:|||:|:.           ||:......|.|.|.
Worm    25 LFAH---SHSKFFATIADSLTDAGHNVTFFTPTIVEKYRNVSYTKSTKDVVHMKP---------- 76

  Fly    87 NSVDLKFFEKR----TFYSHFQE-------------FFLLYDWGKQTCNLTLRSEALQQILRRPG 134
             |..||.:.::    .|..::.|             |..:|:  :|...:......|.::.:|
Worm    77 -SKKLKEYGEQMSTGDFVRYWTEDSTATEIIPVVRIFQKMYN--EQGTVMKDNVGILNELKKR-- 136

  Fly   135 RFDVIIMEQFNTDC--------------MMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHI 185
            :|||||.|.:....              .:.|||.....:              .:|.|::||.:
Worm   137 KFDVIIFEAYIYSAYPLMDYLEIPTFIPSVSVAHDTSLAI--------------EIGEPVMPSVV 187

  Fly   186 PALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQY------KFGHDVPSVGELVKN 244
            ......      ||.:|:  .:..|.|    ...||..|.|:.|      |..::...:..:|..
Worm   188 SDCLSP------FGDKLS--ITERAFN----AFMVPYFDFMIGYPTHRSFKPPYNPIDIRSIVPE 240

  Fly   245 TSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ----KSKPLPADLQRILDNAEEGVILISWGSMIR 305
            .|..|:|.:..:..|:.|....|::|||.:.    :|:.|......|| ...|..:|:|:|||:.
Worm   241 ASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEIL-KLREKTMLVSFGSMLY 304

  Fly   306 ANSLSAAKRDGIIRAVARLKQ-KVIWKWENET---LPNQPPNMHIMKWLPQRDILCHPNVKVFMS 366
            :..:....:..:..|:.:.|. ..|||:|:::   ......|:|..||:||..:|....:..|::
Worm   305 SKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHFAKWVPQTALLADSRLSAFLT 369

  Fly   367 HGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGEN-TVMRALKKAL-DKK 429
            |.||...:|.:|.|.|.:..|...||..|...||.......|:..|:|:: .::.|.:..| |..
Worm   370 HAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGDSEKIVNAFQAILFDSS 434

  Fly   430 FHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLG 494
            :...|..::....::|.:.....:...|..|..|..|.|.|.:.:|:...|:.:||.|:..:||.
Worm   435 YAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFIEYFLIDVAAISMVVLI 499

  Fly   495 SIIASWVWLLRLCCGSSAAQ 514
            :::.....:.::.|..::.:
Worm   500 AVVFVITKMFKILCNKTSVK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	115/506 (23%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	120/522 (23%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	118/533 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740