DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and Ugt36E1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	299/500 - (59%)
Similarity:	379/500 - (75%)	Gaps:	6/500 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAH 73
            :|..|||.   .||..:..|::|||||||.:|||.||||||:|||||||.|.|:|.|.||.|...
  Fly     7 VFCLLALL---SLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNG 68

  Fly    74 YKDFPLTGMDKLTNSVDLKFFEK-RTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRR-PGRF 136
            |||. |.....||:::.|:.||: .:|..|:.|||:|:..|::.||.||.|.||.:||:. ||.:
  Fly    69 YKDH-LLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPPGYY 132

  Fly   137 DVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGR 201
            |||::|||||||.|.|||..|||||.:|||.:|||||||.|||||||:|.|||..|||.|:|.||
  Fly   133 DVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGR 197

  Fly   202 LANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNV 266
            |.||.:.|:||.:||:.:|||.:|:::.:||..:||..:||:|||:..||||:||||||..||||
  Fly   198 LGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNV 262

  Fly   267 IELGGIHIQKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWK 331
            ||:||:||...||||:|||:|||||.:|||||||||.::|.|||||:||||::|:.||:|:||||
  Fly   263 IEVGGVHISPPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWK 327

  Fly   332 WENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNT 396
            :||:||||:|||:||.|||||||||.|||:||||||||||||:||....||:|..|:||||.:|.
  Fly   328 YENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNI 392

  Fly   397 AALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAH 461
            ||||:|||...|..:.:.||||..||.||||..|...||.|:.|:::|.|..|.||||||||||.
  Fly   393 AALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAE 457

  Fly   462 TGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRL 506
            |.||||.:||||.:|||||||||||:|:||.|...:.:.:.|:|:
  Fly   458 TKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRM 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	283/462 (61%)
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	274/456 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471429
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100631at6960
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	10	9.900