DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and Ugt2b

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_113721.5	Gene:	Ugt2b / 24862	RGDID:	3936	Length:	530	Species:	Rattus norvegicus

Alignment Length:	494	Identity:	137/494 - (27%)
Similarity:	239/494 - (48%)	Gaps:	54/494 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKF------FEKRT 98
            ||:.....|:..|.:.||:|:|:.      |.|::...|       ..|.||||      ..|..
  Rat    34 SHWMNIKIILDELVQRGHEVTVLK------PSAYFFLDP-------KKSSDLKFEIFSTSISKDE 85

  Fly    99 FYSHFQEFF--LLYDWGKQTC-----------------NLTLRSEAL--QQILRR--PGRFDVII 140
            ..:||.:..  ..|:..:.||                 .|::..:|:  :|::.:  ..:|||:.
  Rat    86 LQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFDVLF 150

  Fly   141 MEQFNTDCMMGVAHQLQAPVIALSSCVMMPWH--YERMGAPLI-PSHIPALFMAQSQHMNFGGRL 202
            .:.. ..|...:|..|..|.  |.|....|.|  .:.:|..:: ||::|.:....:..|.|..|:
  Rat   151 ADPV-ASCGDLIAELLHIPF--LYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDRV 212

  Fly   203 ANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVI 267
            .|.......::.:::|.....|.......|... :|.|.:....::.:..::.|..|..|.|||.
  Rat   213 KNMICMLYFDFWFEILRHKEWDTFYSEILGRPT-TVDETMSKVEIWLIRSYWDLKFPHPTLPNVD 276

  Fly   268 ELGGIHIQKSKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWK 331
            .:||:|.:.:||||.|::..:.:: |.||::.|.|||:  ::::..|.:.|..|:|::.|||:||
  Rat   277 YIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWK 339

  Fly   332 WENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNT 396
            ::.:|.....||..:.|||||.|||.||..|.|::|||..|..||.|.|:|::..|::|||..|.
  Rat   340 FDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNI 404

  Fly   397 AALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHH-RPQQALHTAIWWVEHVA 460
            |.:|.:|....||...:.:...:.||::.:|..|:....::..:.|| :|.:.|..|::|:|.:.
  Rat   405 AHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIM 469

  Fly   461 HTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIAS 499
            ...||..|:|....:..:.|:||||...| |...::||:
  Rat   470 RHKGAKHLRPLGHNLPWYQYHSLDVIGFL-LTCFAVIAA 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	129/475 (27%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	137/494 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810