Protein Alignment Ugt36D1 and Ugt2b36

DIOPT Version :10

• Sequence 1: NP_609910.1
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001025038.1
• Gene: Ugt2b36 / 231396
• MGIID: 3576103
• Length: 530
• Species: Mus musculus
• Alignment Length: 554
• Identity: 160/554 - (28%)
• Similarity: 268/554 - (48%)
• Gaps: 65/554 - (11%)

  Fly     1 MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVV--- 62
            :|....|||.|.::.     ...:|...||| ::| ...||:.....|:..|.:.||:|:|:
Mouse     2 LWKWISALLLLQISC-----CFRSAKCGKVL-VWP-VDYSHWMNIKIILDELKQKGHEVTVLRPS 59

  Fly    63 -SHF--PDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTF---------YSH-FQEFFLLY-DWG 113
             |.|  |.|.|...::.||.:..:.:...:..|..|:.|:         ||. .|..|..| |:.
Mouse    60 TSIFLDPKKSPGLKFETFPTSFSNDVMEIIFAKAVERWTYEVPRDTCLSYSPLLQNIFDEYSDYC 124

  Fly   114 KQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHY-ERM- 176
            ...|..|:.::.|...|:. .:||||:.:... .|...:|..||.|.  |.|....|.:| |:.
Mouse   125 LTLCKDTVSNKQLMAKLQE-SKFDVILSDAIG-PCGELIAELLQIPF--LYSLRFSPGYYLEKYS 185

  Fly   177 -GAPLIPSHIPALFMAQSQHMNFGGRLAN---------WFST-HALNWMYKLLSVPAADAMVQYK 230
             |.||.||::|.:....|..|.|..|:.|         ||.| ....|          |......
Mouse   186 GGLPLPPSYVPVILSGLSGQMTFKERVKNMICMLYFDFWFQTFREKKW----------DQFYSET 240

  Fly   231 FGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNA-EEG 294
            .|.....: |.:....|:.:..::.|..|..|.|||..:||:|.:.:||||.:::..:.:: |.|
Mouse   241 LGRPTTLI-ETMGKAEMWLIRSYWDLEFPHPTLPNVYYVGGVHCKPAKPLPKEMEDFVQSSGEHG 304

  Fly   295 VILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHP 359
            |::.|.|||:  ::::..|.:.|..|:|::.|||:|:::.:|.....||..|.|||||.|:|.||
Mouse   305 VVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWRFDGKTPATLGPNTRIYKWLPQNDLLGHP 367

  Fly   360 NVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKK 424
            ..|.|::|||..|..||.:.|:|::..|::|:|..|.|.:|.:|....||...:..:.::.||::
Mouse   368 KTKAFITHGGANGLYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDLLNALEE 432

  Fly   425 ALDKKFH-DAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDV--- 485
            .:|..|: :.|..:|...|.:|.:.|..|::|:|.|....||..|:|.|..::.:.|:||||
Mouse   433 VIDNPFYKENAMWLSTIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRPLAYNLTWYQYHSLDVIGF 497

  Fly   486 -YAVLALVLGSIIASWVWLLRLCCGSSAAQKTKK 518
             .|.:..::..|:..::::.|.     ..:|.||
Mouse   498 LLAFVTFIVALIVKCFLFVYRF-----FVKKEKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_609910.1	GT1_Gtf-like	28..457	CDD:340817	136/460 (30%)
Ugt2b36	NP_001025038.1	UDPGT	24..527	CDD:278624	154/527 (29%)