DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-54

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_501996.2	Gene:	ugt-54 / 188885	WormBaseID:	WBGene00012013	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	128/512 - (25%)
Similarity:	218/512 - (42%)	Gaps:	73/512 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKF----------- 93
            ||..|.:..:|.|.:.||.|.:|                   :.:|...|.|||
Worm    29 SHIPFHNTAIKVLLDRGHTVDLV-------------------IAQLNEMVKLKFPNGVGKNYTFG 74

  Fly    94 FEKRTFY----SHFQ-----------EFFLLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQ 143
            :|...||    .|..           ||....|.....|...::...|...::: |.:|:.:...
Worm    75 YEDPNFYRKNAGHLSDIFVEKPIPMAEFLTFDDMTFNLCETVVKDPNLLNYIKQ-GNYDIGLSSD 138

  Fly   144 FNTDCMMGVAHQLQAPVIALSSCVMMPWHYERM---GAPLIPSHIPALFMAQSQHMNFGGRLANW 205
            :: .|...:.|....|  :.:|.|..|....::   |.| .|:.:....:......:|..||
Worm   139 YD-PCANILMHAGGVP--SKASMVPTPLFQPQIVSAGLP-SPASVYGTVLYPKGDDSFFNRL--- 196

  Fly   206 FSTHALNWMYKLLSVPAADAMVQYK------FGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPP 264
              .|.:...|.:..| |...|.:|.      ||...||..|:.:|..:..||.:..:..|:....
Worm   197 --FHLIRHTYNIYFV-APRLMEKYNNLLLETFGPTFPSAEEIERNVDIILVNSNEIIEKPRPVSH 258

  Fly   265 NVIELGGIHIQKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQ-KV 328
            .:..:||:..:|::||..:...||..:.:||:|.|:|:.:..:.:....|...:.|...... ..
Worm   259 KIKYIGGMGKKKAQPLNKEFNDILATSNKGVVLFSFGTQVATSKVPIEIRKNFVTAFKHFPDFSF 323

  Fly   329 IWKWENET----LPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMY 389
            :||::|.|    |.....|:|.::||||.|:|....||.|:||.||....|.:..|:||:|.|::
Worm   324 LWKYDNLTDDAELFADSSNIHRVEWLPQTDLLGDNRVKAFISHMGLNSFLETSAAGIPVLAVPLF 388

  Fly   390 GDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAI 453
            .||..|....|.|.:|.|:....:....::.||:|.| :.|:.:.||::|...:.:|:|:....:
Worm   389 IDQQHNALNAVSRDIGVIVERHQLTVENLVNALQKLLYNPKYGENAKMISKMMNEKPEQSERLFV 453

  Fly   454 WWVEHVAHTGGA-PLLKPSAVEMSRFVYYSLDVYAVLALVL-GSIIASWVWLLRLCC 508
            .|||:.|...|. .::.....|::.|.|||:||..::.|.| .|:|..|..|..:.|
Worm   454 DWVEYAAKNPGLHKIMNLPGAELTPFWYYSVDVILIVVLSLTSSLIIIWKTLSFIKC 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	117/483 (24%)
ugt-54	NP_501996.2	UDPGT	35..507	CDD:278624	124/501 (25%)
ugt-54	NP_501996.2	egt	<218..498	CDD:223071	80/279 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810