DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-10

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504313.2	Gene:	ugt-10 / 188619	WormBaseID:	WBGene00020594	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	544	Identity:	137/544 - (25%)
Similarity:	220/544 - (40%)	Gaps:	103/544 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LKVLGLFP----------HP--GVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLT 80
            |.:|.:||          :|  |.||..|...:...:|:.||:|:|...|          ...|.
Worm     8 LLILCVFPIILGKNILIFNPIFGFSHVKFVSKLADIIADHGHNVTVFQPF----------HIALK 62

  Fly    81 GMDKLTNSVDLKFFEKRTFY-SHFQEF-------FLLYDWGKQTCN-----LTLRSEALQQILRR 132
            ..:.|..:.::||.   .:| .|:.|.       |.:: |.....|     ..:.::||.....|
Worm    63 NTEGLIKNKNIKFI---NYYPDHYDELLKTETQTFPMF-WDSHLMNNPVVSAVMMAKALSSTFER 123

  Fly   133 PG----------------RFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLI 181
            ..                :|||:|.|.|....|. |||.:..|.|.:.|.|......:..|.|..
Worm   124 TATQLVKDQNVLNNLKSKKFDVMISETFELTGMY-VAHLINVPCIPIWSAVRFLVFNKAFGQPST 187

  Fly   182 PSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYK-LLSVPAADAMVQYK-------FGHDVPSV 238
            ..:||......:....|..|         ||.:|: .......|.:.||:       .||.||..
Worm   188 LGYIPLEGSKMAPDFGFFDR---------LNDVYRDFFGQIGMDRLGQYQNNIIEKAVGHSVPYW 243

  Fly   239 GELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSK-----PLPADLQRILDNAEEGVILI 298
            .:||..:.::..|.:..|.....|.|.::.:|||.|...|     .||.:.::||.. .|..:||
Worm   244 KDLVSQSPIYITNSNPYLDFAVATTPAIVHIGGITIDLEKIKHADELPEEYEKILQE-RESTVLI 307

  Fly   299 SWGSMIRANSLSAAKRDGIIRAVARLKQ-KVIWKWENETLPNQ---PPNMHIMKWLPQRDILCHP 359
            |:||:||:..:....:.|:|:....|.. ..|||:|.:.:..|   |.|:|:.||:||..:|...
Worm   308 SFGSVIRSYEMPDNFKAGLIKMFESLPDVTFIWKYERDDVEFQKRLPKNVHLKKWVPQPSLLADK 372

  Fly   360 NVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDI--GENTVMRAL 422
            .||:|::||||..|.|.||.|.|.::.|::|||..|...|...|.....:..|:  ||.......
Worm   373 RVKLFVTHGGLGSTMEVAYTGKPALSVPIFGDQPENADMLARHGGAIAYDKFDLANGEKLTKTVR 437

  Fly   423 KKALDKKFHDAAKVVSHSFHHRP-------QQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVY 480
            :...:.||...|:.:......:|       .:.|..|:.:..|.:..       |:..::....:
Worm   438 EMVTNPKFSKNAEALRDVLLKQPIDPKMNLMKHLEFAMEFPNHRSQV-------PAINKLGWIAH 495

  Fly   481 YSLDVYAVLALVLGSIIASWVWLL 504
            |.|||.|.|.||    :..:::|:
Worm   496 YYLDVIAFLTLV----VVGFLYLI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	128/520 (25%)
ugt-10	NP_504313.2	egt	1..463	CDD:223071	124/479 (26%)
ugt-10	NP_504313.2	UDPGT	31..535	CDD:278624	131/521 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161471
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740