DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-20

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_500913.1	Gene:	ugt-20 / 187130	WormBaseID:	WBGene00019516	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	134/550 - (24%)
Similarity:	223/550 - (40%)	Gaps:	64/550 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLFLALALSQPDELVEAAGPLKVL---GLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKH 69
            |||.|:..         |...|:|   .||.|   ||..|.......|.:|||:|:|:....||
Worm     6 LLFSAICF---------ASSYKILFYTNLFGH---SHVKFLGAAADTLTDAGHNVTVLIPVFDK- 57

  Fly    70 PVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCN-LTL--RSEALQQILR 131
                   ...|.:....|.:.|:..|....:...:...|...|.:...| ||:  :.|.:.:|..
Worm    58 -------ALKTSLKSTKNVIMLQPTEDIANFVKGRATMLKNIWLQDNTNPLTMIKKVETMSKIFS 115

  Fly   132 ----------------RPGRFDVIIMEQFNTDCMMGVAHQLQAPV-IALSSCVMMPWHYERMGAP 179
                            :...:|:.|.|.|:| |.......::... :|:.|........:.:|.|
Worm   116 SQCKRVLSETDIIEKLKAENYDLAITEPFDT-CAYEFFEAIETRTHVAILSASRYDHVSDVIGQP 179

  Fly   180 LIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKN 244
            ...|:.|.|..:....|....||.|.....|.::.:..  |...||.|..:......|..|.:..
Worm   180 AAASYNPGLLSSNGDQMTMPQRLLNLIQYAAGSYFFSY--VGDKDAEVAKEINPKWRSWRETLPE 242

  Fly   245 TSMFFVNQHYSLSGPKVTPPNVIELGGIHI---QKSKPLPADLQRILDNAEEGVILISWGSMIRA 306
            .|....||...|..|..|...:|.:||:.:   :||..|.....:|||..::.| .||:||..|:
Worm   243 ASFIMTNQIPLLDFPAPTFDKIIPIGGLSVKTDKKSLKLEEKWSKILDIRKKNV-FISFGSNARS 306

  Fly   307 NSLSAAKRDGIIRAVARLKQKV-IWKWE--NETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHG 368
            ..:....:...::.:..:.... |||:|  |:.......|:::..||||.::|....:.||::||
Worm   307 VDMPLEYKKTFLQVIKSMPDTTFIWKYEDLNDKFTEGIENVYLGDWLPQNELLADKRLNVFVTHG 371

  Fly   369 GLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGE-NTVMRALKKAL-DKKFH 431
            ||...:|.:..|.|.|..|::.||..|...|...|...:|...|:.. ..|...::|.: :.::.
Worm   372 GLGSVTELSMMGTPAVMIPLFADQSRNAQMLKRHGGAAVLVKNDLSNPKLVQETIEKVINNSEYR 436

  Fly   432 DAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSI 496
            ..|:.:|...::.|.....|.:.:||..|..|..|.|.....:.|...|:.||:.|:..|:  ::
Worm   437 KNAERLSEMLNNLPTNPRETLVKYVEFAARFGKLPSLDNYGRQQSFVEYFFLDIIAIFILI--TL 499

  Fly   497 IASWV------WLLRLCCGS-SAAQKTKKD 519
            |..:|      :..|.|.|| :..||:||:
Worm   500 IFLYVSFRIVKFAFRKCIGSRNIDQKSKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	116/491 (24%)
ugt-20	NP_500913.1	UDPGT	29..518	CDD:278624	118/502 (24%)
ugt-20	NP_500913.1	egt	<268..500	CDD:223071	61/234 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790