DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-19

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_500912.2	Gene:	ugt-19 / 187129	WormBaseID:	WBGene00019515	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	538	Identity:	130/538 - (24%)
Similarity:	231/538 - (42%)	Gaps:	65/538 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 AGPLKVL---GLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLT 86
            |...|:|   .||.|   ||..|.......|.:|||:|:||.      ||  :.|...|.:....
Worm    17 ASSYKILFYTNLFGH---SHVKFLGAAADILTDAGHNVTVVM------PV--FDDSIKTSLKSTK 70

  Fly    87 N------SVDLKFFEK-RT-------FYSHFQEFFLLYDWGKQT------CNLTLRSEALQQILR 131
            |      |.|:..|.| ||       ...:...|.:|...|..:      |...|.:..|.:.::
Worm    71 NIIFVNSSDDVAAFAKARTKMLNNLWTMDNTNPFTMLTRVGMMSNTFSSQCKKVLTNTELIETMK 135

  Fly   132 RPGRFDVIIMEQFNTDCMMGV--AHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQ 194
            .. .:|:.:.|.|:. |....  |..::|.|..|||. .:....:.:|.|..||:.|.|....|.
Worm   136 AE-NYDLAVTEPFDL-CAYPFFEAINIRAHVGILSSS-RLDHVSDVIGQPAAPSYNPGLMSTNSD 197

  Fly   195 HMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVP---SVGELVKNTSMFFVNQHYSL 256
            .|....|..|.......::.:..:....|:.:.:..     |   |..|:|...|....||...|
Worm   198 RMTMWQRFVNVIQYACGSYFFSYIGDREAEVVKEIN-----PKWRSWREVVPEASFIMTNQIPLL 257

  Fly   257 SGPKVTPPNVIELGGIHI---QKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGII 318
            ..|..|...:|.:||:.:   :||..|.....:|||..::.| .||:||..|:..:....::..:
Worm   258 DFPAPTFDKIIPIGGLSVKTDKKSLKLEEKWSKILDIRKKNV-FISFGSNARSVDMPLEYKNTFL 321

  Fly   319 RAVARLKQKV-IWKWE--NETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCG 380
            :.:..:.... |||:|  |:.......|:::..||||.::|....:.||::||||...:|.:..|
Worm   322 QVIKSMPDTTFIWKYEDLNDKFTEGIENVYLGDWLPQNELLADKRLNVFVTHGGLGSVTELSMMG 386

  Fly   381 VPVVATPMYGDQFVNTAALVERGMGTILNFEDIGE-NTVMRALKKALDK-KFHDAAKVVSHSFHH 443
            .|.|..|::.||..|...|...|...:|...|:.: ..|...:::.|:. ::..:|:.|:....:
Worm   387 TPAVMIPLFADQSRNGQMLKRHGGVAVLKKTDLSDAKLVQSTIEEVLNNPEYRKSAERVAEMLRN 451

  Fly   444 RPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWV------W 502
            :|.....|.:.:||..|..|..|.:.....:::...|:.||:.::::|:  :::..::      .
Worm   452 QPTNPKETFLKYVEFTARFGKLPSMDNYGRQLTFVQYFFLDIISIISLI--TVVFLYISYKVIRC 514

  Fly   503 LLRLCCGS-SAAQKTKKD 519
            .::.|.|| |:.:|:||:
Worm   515 TIKKCFGSRSSEEKSKKE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	120/492 (24%)
ugt-19	NP_500912.2	egt	1..472	CDD:223071	117/474 (25%)
ugt-19	NP_500912.2	UDPGT	32..521	CDD:278624	118/507 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790