DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-8

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504315.1	Gene:	ugt-8 / 186768	WormBaseID:	WBGene00019234	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	537	Identity:	145/537 - (27%)
Similarity:	222/537 - (41%)	Gaps:	112/537 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LKVLG--------LF-PHPGVSHFHFFHPIMKGLAEAGHDVS----------------------V 61
            |.|||        :| |..|:||..|...:...:|:.||:|:                      :
Worm    10 LLVLGSVSCKNILIFNPIFGLSHVKFISKMANIIADHGHNVTLFQPFHIALKNTEGLIKNKYIEI 74

  Fly    62 VSHFPDKHPVAHYKD--------FPLTGMDKLTNSVDLK-FFEKRTFYSHFQEFFLLYDWGKQTC 117
            ::::||     ||.:        ||......|.|:..|. |...:.....|:          :|.
Worm    75 INYYPD-----HYDELLKTETATFPAFWDSHLMNNPVLSAFMIPKAIAGEFE----------RTA 124

  Fly   118 NLTLRSE-ALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLI 181
            ...|:.: ||..:..|  .|||||.|.|....|. :||.|..|.|.:.|.|.........|.|..
Worm   125 TQLLKDKVALDDLKSR--NFDVIISETFELTGMY-IAHMLNVPCIPVWSAVRFTIFNNIFGQPSS 186

  Fly   182 PSHIPALFMAQSQHMNFGGRL----ANWFSTHALNWMYKLLSVPAADAMVQYK-------FGHDV 235
            ..:....|...:....|..||    .|:|.|..:            |.|.||:       .|..:
Worm   187 LGYSQQPFSKLAPEAGFIDRLNDVYRNFFFTITM------------DGMGQYQNDFIEKAVGRPL 239

  Fly   236 PSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGG--IHIQKSK---PLPADLQRILDNAEEGV 295
            |...:|:|...::|.|.:..|.....|...::.:||  :.::|.|   |||....:||:. .|..
Worm   240 PYWKDLIKEAPVYFTNSNEYLDFAVPTTATIVHIGGFTMDLEKMKHVDPLPDKYAKILEE-REST 303

  Fly   296 ILISWGSMIRANSLSAAKRDGIIRAVARLKQ-KVIWKWENETLPNQ---PPNMHIMKWLPQRDIL 356
            :|||:||:||:..:....:.|||:....|.. ..|||:|.:.:..|   |.|:|:.||:||..:|
Worm   304 VLISFGSVIRSYQMPDNFKAGIIKMFESLPDVTFIWKYERDDVEFQKKLPKNVHLKKWVPQHSLL 368

  Fly   357 CHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTIL--NFE--DIGENT 417
            ....||:|::||||..|.|.||.|.|.:..|::|||..|...|...| |.|.  .||  | ||..
Worm   369 ADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENANMLARHG-GAISYDKFELAD-GEKL 431

  Fly   418 VMRALKKALDKKFHDAA----KVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLK---PSAVEM 475
            .:.......:.|::..|    ||:||       |.:...:..::|:......|.|:   |:..:|
Worm   432 AITIRDMVRNPKYNKNAQELLKVLSH-------QPIDPKLNLMKHLEFAMEFPNLRSQVPAINQM 489

  Fly   476 SRFVYYSLDVYAVLALV 492
            ....:|.|||...|:|:
Worm   490 GLIAHYYLDVIFFLSLI 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	139/525 (26%)
ugt-8	NP_504315.1	UDPGT	30..516	CDD:278624	138/517 (27%)
ugt-8	NP_504315.1	egt	<284..462	CDD:223071	65/187 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740