DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-34

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_505728.2	Gene:	ugt-34 / 185120	WormBaseID:	WBGene00009255	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	136/543 - (25%)
Similarity:	225/543 - (41%)	Gaps:	62/543 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAH 73
            |||...|.|   |..:...|....||.|   ||..|...|...|.||||:|:.:.      |:.|
Worm    10 LFLLHLLPQ---LTLSYNYLVFCPLFAH---SHHKFLAKIADTLTEAGHNVTFLM------PIIH 62

  Fly    74 --YKDF-------------PLTGMDKLTNSVDLKFFEKR-----TFYSHFQEFFLLY----DWGK 114
              |::.             |...::::..:.|...|.|.     ||....:.||.::    |..|
Worm    63 REYENVKYLEHTTDIVYIQPDKELEEIAQNADYSTFWKNDFGILTFIPAIERFFRMFTKVHDILK 127

  Fly   115 QTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALS-SCVMMPWHYERMGA 178
            :..::      |..:..|  :||.:|.|.. ..|...:...|:...|..| |...|....:.:|.
Worm   128 KDLSV------LDNLKNR--KFDAMIFESL-AFCAHPIREYLEIKTIFPSWSMTHMTELSQAIGE 183

  Fly   179 PLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVK 243
            |..|:.:|.........|.|..||.|..:......:::      ...:..:|:.|......|::.
Worm   184 PSSPTFLPITISPFGDKMTFKERLLNTLADFTFTHIFQ------PPTLTSFKYPHQTFDFKEILS 242

  Fly   244 NTSMFFVNQHYSLSGPKVTPPNVIELGGIHI----QKSKPLPADLQRILDNAEEGVILISWGSMI 304
            .....|.|.:..|..|:.|....||:|||.:    .:.:.||.:...|| |.::..:|||:|||:
Worm   243 QAPFIFFNSNPFLDFPRPTLTKTIEIGGISVNATLMRLEKLPEEYNTIL-NLKQQNVLISFGSML 306

  Fly   305 RANSLSAAKRDGIIRAVARLKQ-KVIWKWENETL--PNQPPNMHIMKWLPQRDILCHPNVKVFMS 366
            |::.:....:|.|.:.|..... ..|||:||..:  ....||.|..||:||..:|....:..|::
Worm   307 RSSEMPVEYKDTIAQVVRSFPSVTFIWKYENNNVEFAENLPNFHFFKWVPQTALLADSRLSAFIT 371

  Fly   367 HGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL--DKK 429
            |.||...:|.:|.|.|.:..|::.||..|...||.......|:.:|:|:..|:|....|:  ||.
Worm   372 HAGLGSINELSYIGKPAILVPIFADQLRNAKMLVRHNGSIELDKKDLGKFDVLRDAVDAILNDKS 436

  Fly   430 FHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLG 494
            :.:.|.::|.....:|.......:.:.|..|..|..|.|.|...:||.|.::.:|:...|.....
Worm   437 YTNNAILLSQQLESQPFSPHDLLVKYAEFGAKFGELPSLDPHYRKMSFFSFFMIDIILFLTATFA 501

  Fly   495 SIIASWVWLLRLCCGSSAAQKTK 517
            ..::..::|.|:...|...:|.|
Worm   502 IFVSISLYLFRVFFKSVFVRKEK 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	124/494 (25%)
ugt-34	NP_505728.2	UDPGT	35..518	CDD:278624	123/504 (24%)
ugt-34	NP_505728.2	Glycosyltransferase_GTB_type	<248..500	CDD:299143	74/252 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740