DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-41

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504818.2	Gene:	ugt-41 / 184295	WormBaseID:	WBGene00017336	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	563	Identity:	149/563 - (26%)
Similarity:	235/563 - (41%)	Gaps:	90/563 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVV-----SHFPD 67
            |:.|.|.||     :........|.:.|..|.||..|...:...|.||||:|:|:     |.|.:
Worm     4 LIILLLVLS-----ISNTSGFNYLVVSPAFGHSHSTFMGKLADSLTEAGHNVTVLSIIISSKFRN 63

  Fly    68 KHPVAHYKDFPL----TGMDKLTNSVDLKFFEK---------RTFYSHFQEFFLLYDWGKQTCNL 119
            .......||..:    |..|:||.:::...|.:         .|..|:.....:..|..|
Worm    64 ISYTKSTKDIVVVETTTEQDQLTENMENDDFARYWTQEGTMLETIPSYLMFLKMAEDGYK----- 123

  Fly   120 TLRSEALQQI----LRRPGRFDVIIMEQFNTDCMMGVAHQ--LQAPVIALSSCVMMPWHY-ERMG 177
            |.|..||.|:    ..|| ::|.:..|.|   ..||.|.|  |:.||....:.:...:.: |.:|
Worm   124 TFRDHALPQMDYLKNNRP-QYDAVFFESF---FFMGKAIQEYLEIPVFLPVTSITHDYRFAELIG 184

  Fly   178 APLIPSHIPALFMAQSQHMNFGGRLANWFSTHA-------LNWMYKLLSVPAADAMVQYKFGHDV 235
            .|:.||::...|......|||..||.|..|.:.       .||  |.|..|:.|.:|:.:: |..
Worm   185 EPVSPSYLSGYFTNFGNIMNFQERLTNTISYYLGQILIAFPNW--KTLQDPSKDLLVESEY-HRA 246

  Fly   236 PSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ----KSKPLPADLQRILDNAEEGVI 296
            |.|          |:|.:..:..|:......||:|||.:.    ||:.:......||......|
Worm   247 PYV----------FINSNPYIDFPRPLLSKTIEIGGITVDVKKLKSEKVDEKWDNILKKRPHNV- 300

  Fly   297 LISWGSMIRANSLSAAKRDGIIRAVARLKQ-KVIWKWENE--TLPNQPPNMHIMKWLPQRDILCH 358
            |||:|||.::..:....::.:::.:...|. ..|||:|:|  :..|...|:...||:||..:|..
Worm   301 LISFGSMFKSIYMPDFYKENMVKVMKSFKNVSFIWKYESEETSFANGAENIIFSKWVPQTALLAD 365

  Fly   359 PNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTI----LNFEDIGENTVM 419
            ..:..|.:||||...:|.:|.|.|.:..|::.||..|:..|. |..|:|    .|.|:.  ||:.
Worm   366 SRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQIRNSKMLT-RHNGSIEISKFNLENY--NTLR 427

  Fly   420 RALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSL 483
            .||...| .:.:.:.|:.::....::|.:.....:...|..|..|..|....:...|....||.|
Worm   428 SALHSILFAESYSENAEKLAKKLEYQPTKPKELFVRHAEFAARFGEQPAQDSNLRTMGFAAYYLL 492

  Fly   484 DVYAVLA-------LVLGSIIASWVWLLRLCCGSSAAQKTKKD 519
            ||.|.|.       .|:..:|...|.||.:        |:|:|
Worm   493 DVIAFLTSFVLLVIFVVFIMIRQIVKLLTI--------KSKRD 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	130/504 (26%)
ugt-41	NP_504818.2	UDPGT	22..510	CDD:278624	137/513 (27%)
ugt-41	NP_504818.2	Glycosyltransferase_GTB_type	26..512	CDD:299143	136/511 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161519
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.740