DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-38

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504812.1	Gene:	ugt-38 / 184294	WormBaseID:	WBGene00017333	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	133/545 - (24%)
Similarity:	222/545 - (40%)	Gaps:	99/545 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHP 70
            :||||...|      .|.:...|....||.|   ||..||..|...|.:|||:|:..:      |
Worm     4 LALLFTLYA------NVSSFNFLVFCPLFAH---SHSKFFATIADSLTDAGHNVAFFT------P 53

  Fly    71 --VAHYKDFPLTGMDK----LTNSVDLKFFEKR----TFYSHFQE-------------FFLLYDW 112
              |..|::|..|...|    :..|..||.:.::    .|..::.|             |..:|:
Worm    54 IIVEKYRNFNYTKSTKDVVYMEPSKKLKEYGRQMSTGDFVRYWTEDSTATEIITVVRIFQKMYN- 117

  Fly   113 GKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDC--------------MMGVAHQLQAPVIAL 163
             :|...:....|.|..:.:|  :|||||.|.|....              .:.|||.....|
Worm   118 -EQGTVMKDNIEILNDLKKR--KFDVIIFEAFIFSAYPLMDYLEIPTFIPSLSVAHDTALAV--- 176

  Fly   164 SSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQ 228
                       .:|.|::||.:......      ||.:|:  .:..|.|    ...||..|.|:.
Worm   177 -----------EIGEPVMPSVVSDCLSP------FGDKLS--ITERAFN----AFMVPYFDFMIG 218

  Fly   229 Y------KFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ----KSKPLPAD 283
            |      |..::...:..:|...|..|:|.:..:..|:.|....|::|||.:.    :|:.|...
Worm   219 YPTHRSFKPPYNPIDIRSIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDET 283

  Fly   284 LQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQ-KVIWKWENET---LPNQPPNM 344
            ...|| ...|..:|:|:|||:.:..:....:..:..|:.:.|. ..|||:|:::   ......|:
Worm   284 WSEIL-KLREKTMLVSFGSMLYSKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENI 347

  Fly   345 HIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILN 409
            |..||:||..:|....:..|::|.||...:|.:|.|.|.:..|...||..||..||.......|:
Worm   348 HFAKWVPQTALLADSRLSAFLTHAGLGSITELSYLGKPAILCPQLFDQMRNTKMLVRHNGSIELS 412

  Fly   410 FEDIGEN-TVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSA 472
            ..|:|:: .::.|.:..| |..:...|:.::....::|.:.....:...|:.|..|..|.|.|.:
Worm   413 KYDLGKSEKIIEAFQAILFDSSYAKNAQKLAEQLENQPIKPKEMMVKHAEYAARFGRLPSLDPYS 477

  Fly   473 VEMSRFVYYSLDVYAVLALVLGSII 497
            .:||...|:.|||.|:...:|..::
Worm   478 RKMSFVEYFLLDVAAICVFILTFVV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	123/513 (24%)
ugt-38	NP_504812.1	Glycosyltransferase_GTB_type	12..512	CDD:299143	129/537 (24%)
ugt-38	NP_504812.1	UDPGT	29..521	CDD:278624	123/511 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161418
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740