DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-15

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506211.1	Gene:	ugt-15 / 183462	WormBaseID:	WBGene00008097	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	132/540 - (24%)
Similarity:	215/540 - (39%)	Gaps:	103/540 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKL 85
            |:|.....|||...|..|.||.:|...|...|.:|||||:::.      ||.......|.|..|:
Worm    11 LLELVCSYKVLVFNPAFGASHSNFLGKISDILIDAGHDVTMLI------PVCMESKKDLVGSKKV 69

  Fly    86 TNSVDL------KFFEKRT-------------------FYSHFQEFFLLYDWGKQTCNLTLRSEA 125
            ...:.:      |..::..                   |:|..:.|.:..  |.|..|:..::..
Worm    70 KKIIRIDQEPRSKLMQEEAKTEEMIKKQIWKLDADITIFFSMIKNFSIAS--GYQCENIFKQTAI 132

  Fly   126 LQQILRRPGRFDVIIMEQ-----FNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHI 185
            |:|:  |...||:.|.|.     |.....:||     ..:|...|.:.:......:|.|...|:.
Worm   133 LEQL--RNEHFDLGITESLFICGFPLLDSIGV-----KTIINADSVLYLDVVKHALGEPASTSYY 190

  Fly   186 PALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGEL--------- 241
            |.::......|:|..|:.|.|.. |.:|.:         :..:::        |||
Worm   191 PGVYAKNIDRMSFRERVRNLFGM-AFSWYF---------SWTRFQ--------GELEAIKPYYNK 237

  Fly   242 -------VKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILD---NAEEGVI 296
                   :...:.:|:|.:..|..|..|.|..:.:||:.:..:|.....|::..|   |..:..:
Worm   238 SLTWEDHINGAAYYFINSNQYLDYPSPTLPKTVFIGGMQVNTNKHGKVKLEKEWDDLLNLRKQNV 302

  Fly   297 LISWGSMIRANSLSAAKRDGIIRAVARLKQKV-IWKW--ENETLPNQPPNMHIMKWLPQRDILCH 358
            |:|:||...:..:....::..::..|.:.:.. |||:  ||.||.:|..|:.:..|:||.|||..
Worm   303 LVSFGSNAFSCDMPDEFKESFLKVFASMPETTFIWKYEQENATLADQLSNVKLTTWMPQNDILAD 367

  Fly   359 PNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTIL------NFEDIGE-- 415
            ..:.:|::||||..:.|.||.|.|.|..|:..||..|...|...|....|      |.|.|.|
Worm   368 ERLTLFVTHGGLGSSMELAYQGKPAVVIPLMADQPRNALMLTRHGGALQLDKTFLNNSEKIREAI 432

  Fly   416 NTVMR--ALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRF 478
            .|||.  :.||..:|    .|.::|...|......|....:.|:|    |....|......::.|
Worm   433 QTVMENPSYKKNAEK----LANILSSQPHQPKDVVLKHCDFAVKH----GDLKTLNSEGRHLNVF 489

  Fly   479 VYYSLDVYAVLALVLGSIIA 498
            .|||:|:.....|.|.:||:
Worm   490 QYYSIDIALAAGLFLVTIIS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	125/522 (24%)
ugt-15	NP_506211.1	UDPGT	19..506	CDD:278624	128/527 (24%)
ugt-15	NP_506211.1	Glycosyltransferase_GTB_type	<252..493	CDD:299143	70/248 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790