DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-7

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	564	Identity:	138/564 - (24%)
Similarity:	240/564 - (42%)	Gaps:	88/564 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDV-----SVVSHFPD 67
            |:||...|       :.:...|.|.:.|....||..|...|...||:.||:|     .:|....|
Worm     3 LVFLTFFL-------QYSYAFKYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRD 60

  Fly    68 KHPVAHYKDFPLTGMDKLTNSVDLKF--FEKRT----FYSHFQEFFLLYDWG------------- 113
            |               |:..:.|:|.  :|..|    ||.:..:..:...|.
Worm    61 K---------------KVIKNPDIKIINYEANTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQF 110

  Fly   114 --------KQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAP--VIALSSCVM 168
                    :..|......::|..:|:.. .|||::.|.|: .|.:.:...|:.|  ::|::|..:
Worm   111 AEAMSKDLEHMCLQVFEDKSLHTMLKSE-HFDVLLAEPFD-PCGLYLGDYLKIPSTIVAMASSRI 173

  Fly   169 MP--WHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKF 231
            .|  |   .:|.|...:.||.......:......|:.|.:.......|::.:.....|.: ::|.
Worm   174 DPVQW---ALGQPSGLNFIPGPDSKYGEESGVWDRINNVWMFFMRTRMFRAVYWNLLDKL-RFKT 234

  Fly   232 GHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ----KSKPLPADLQRILDNAE 292
            |.::.::.|:|..::..|.|.:..|..|..:....:.:||..:.    ||:.||.:|:.||.. .
Worm   235 GLEIRNIDEIVAESAYLFYNSNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPENLKNILQK-R 298

  Fly   293 EGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKV--IWKWEN----ETLPNQPPNMHIMKWLP 351
            ...:.||:||:||:..:....::.||. |.:|...|  |||:|:    |...|.|.|:|:|||||
Worm   299 PNTVFISFGSVIRSADMPQEYKNAIIE-VTKLMSDVTFIWKYEDEKDEEMRGNIPENVHLMKWLP 362

  Fly   352 QRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGEN 416
            |..:|....|.:|::||||....|.||.|.|.:..|::.||.:|...|...|...:.:..::..
Worm   363 QPALLADSRVSLFITHGGLGSIMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAEVYSKFELSN- 426

  Fly   417 TVMRALKKAL-----DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMS 476
              .:.|||.:     :.|:...||.:|:....:|...:...:...|..|.....|.|.|.:..::
Worm   427 --AKKLKKVIQNMIQNPKYLANAKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLN 489

  Fly   477 RFVYYSLDVYAVLALVLGSIIASWV-WLLRLCCGSSAAQKTKKD 519
            .|.::.||:.|.| |:|..:.|.:| |:..:.|  |...|:|.:
Worm   490 FFQFFFLDIVATL-LILFMLSALFVYWITYVIC--SVRSKSKME 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	121/511 (24%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	121/506 (24%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	127/520 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740