DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-50

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_741913.1	Gene:	ugt-50 / 181413	WormBaseID:	WBGene00011564	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	528	Identity:	122/528 - (23%)
Similarity:	220/528 - (41%)	Gaps:	74/528 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHD----VSVVSHFPDK 68
            :.|...||.....:|.||   |:|...|....||..........|..||||    :...|...|.
Worm     9 MFFCLTALLHGSFIVNAA---KILVYCPSISKSHVLLCSKYADLLHNAGHDTVLFIPSYSKLLDN 70

  Fly    69 HPVA-HYKDFPL--------TGMDKLTNSVD---LKFFEKRTFYSHFQEFFLLYDWGKQTCNLTL 121
            :..| |.|.:.|        |.:..|.|.::   :.|.::.||.:.|        |.....:|..
Worm    71 YDGAKHAKVWRLHNVTEAYDTKLGTLANVMENSHIGFIDRLTFDADF--------WIDMCADLLG 127

  Fly   122 RSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAP--VIALSSCVM--MPWHYERMGAPLIP 182
            :...:|.|:  ..:||::|..:.: .|...:......|  |:..|..:|  :.|:   :|.|.:|
Worm   128 KLPEMQHII--DYKFDLVIYNEID-PCTPAIVRLFNIPKTVLLSSEAIMDKVAWN---LGLPTLP 186

  Fly   183 SHIPALFMAQSQH--MNFGGRLANWF------------STHALNWMYKLLSVPAADAMVQYKFGH 233
            |::|:: .....|  |:|..|::|.:            ..|.||...|.:|             .
Worm   187 SYVPSV-EENPNHDRMSFFERMSNVYKFFQSIVVHYLQDIHVLNLFRKEVS-------------S 237

  Fly   234 DVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSK--PLPADLQRILDNAEEGVI 296
            |.||:.|:::|.|:..||.......|:......:.:|.:...|.:  .||..........:.|.:
Worm   238 DFPSIAEIIRNVSLVLVNTDEIFDLPRSYSSKFVYVGMLEAGKDENVTLPKKQDDYFKKGKSGSV 302

  Fly   297 LISWGSMIRANSLSAAKRDGIIRAVARLKQK--VIWKWENETLPNQ----PPNMHIMKWLPQRDI 355
            .:|:|::....||....:..|:.|:.:|...  |:....::....|    ..|:.::.|:||:.:
Worm   303 FVSFGTVTPFRSLPERIQLSILNAIQKLPDYHFVVKTTADDESSAQFFSTVQNVDLVDWVPQKAV 367

  Fly   356 LCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMR 420
            |.|.|:|:|:||||:....|..|.|||:|..|::.|||.|...:..||.|.::..|.:.:.|...
Worm   368 LRHANLKLFVSHGGMNSVLETMYYGVPMVIMPVFTDQFRNGRNVERRGAGKMVLRETVVKETFFD 432

  Fly   421 ALKKALDKK-FHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLD 484
            |:...|::| :..:.|.:||...::|..:......|::.|.....:......:..:|...:..||
Worm   433 AIHSVLEEKSYSSSVKRISHLMKNKPFTSEERVTKWIDFVLKYETSEHFDLESNNLSIIEHNHLD 497

  Fly   485 VYAVLALV 492
            ::..|.::
Worm   498 LFFYLCII 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	116/503 (23%)
ugt-50	NP_741913.1	egt	9..475	CDD:223071	118/496 (24%)
ugt-50	NP_741913.1	UDPGT	26..520	CDD:278624	117/511 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810