DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-5

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506200.1	Gene:	ugt-5 / 179753	WormBaseID:	WBGene00013906	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	574	Identity:	145/574 - (25%)
Similarity:	237/574 - (41%)	Gaps:	110/574 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVS-----VVSHF 65
            |.|:|:.|       .::.......|.:.|..|.||......|...||:|||.|:     ||..|
Worm     6 VFLIFVLL-------FIKNVASYNFLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVVELF 63

  Fly    66 PD----KHP---VAHY-------KDFPLTGMDKLTNS---------VDLKFFEKRTFYSHFQEFF 107
            .|    |:|   :.:|       |:.|  |...|:::         |..|.|..|..:..|||.
Worm    64 KDHDLIKNPNIEIMNYFHDEEGKKNIP--GHSVLSDAWTSYKYQSDVGQKIFAPRILHQSFQEM- 125

  Fly   108 LLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVI----------A 162
                     |......|||.:.| :..:|||::.|.|:. |.:.:|..|:.|.|          |
Worm   126 ---------CRHMFEDEALHRQL-KDKKFDVVLSETFDF-CGLYLADYLEMPAIISVFTGNRLNA 179

  Fly   163 LSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMV 227
            :::.         :|.|....::|:...:.:.:|:...|..|:       | :|:||......:
Worm   180 ITNA---------LGEPSFLHYLPSPSSSFNANMSLYDRFNNF-------W-HKILSSSTFGEL- 226

  Fly   228 QYKFGHDVPSVGELVKNTSMFF------VNQHYSLSGPKV-----TPPNVIELGG--IHIQKSKP 279
               |......|..|....:..:      |..|:|.|.|.:     |...||.:||  :..::..|
Worm   227 ---FDRQYADVYRLTNGKARHWKQILNDVTYHFSNSNPYLDFVIPTIAKVIPIGGYTMDYKQVPP 288

  Fly   280 LPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQ-KVIWKWENE----TLPN 339
            :..||..|| |.....:.||:|:||.|..:....:..:|......|. ..:||:|..    ...|
Worm   289 VSKDLDTIL-NLRSSTVFISYGTMISAKYMPDEYKQSMIDFFKDNKNVTFLWKYEEPEEKFIKEN 352

  Fly   340 QPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGM 404
            .|.|:|:..|.||:.:|....||:|::||||..|.|.||...|.:.||::.||..|...|...|.
Worm   353 IPDNVHLSTWFPQQSLLADKRVKLFITHGGLGSTMELAYSAKPAIVTPLFADQPSNAQMLERHGS 417

  Fly   405 GTILNFEDIGENTVMRALKKAL--DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPL 467
            ..:|:..||........|.|.:  |||:.:||..::...:::|.......:...|:.|..|..|.
Worm   418 VEVLSKHDIPNWKKQSDLLKTMLADKKYQEAATRLADILNNQPISPRELMLKHAENAARFGKIPS 482

  Fly   468 LKPSAVEMSRFVYYSLD--VYAVLALVLGSIIASWVW-LLRLCCGSSAAQKTKK 518
            |.|.|.:|....:|::|  :|:|...:....:...:: :::.||      ||:|
Worm   483 LTPFAKDMGFIEFYNIDLIIYSVSFTLFAIYVTIEIFGIVKNCC------KTRK 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	132/518 (25%)
ugt-5	NP_506200.1	egt	6..509	CDD:223071	140/545 (26%)
ugt-5	NP_506200.1	UDPGT	32..527	CDD:278624	135/536 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161332
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740