DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-2

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_505672.2	Gene:	ugt-2 / 179450	WormBaseID:	WBGene00007073	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	133/539 - (24%)
Similarity:	239/539 - (44%)	Gaps:	82/539 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKH- 69
            :..||.||..:     |.|...|.|..:|   |.||..|.:.:...||...|:|:::..:..:|
Worm     6 LVFLFFALYCN-----VLAYNYLVVAPVF---GYSHMKFMNKVADTLANGKHNVTLLQTYIYEHW 62

  Fly    70 ---PVAHYKDFPLTGMDKLTN-------SVDLKFFEKRTFYSH-----FQEFFLLYDWGKQTCNL 119
               .:...|:..:.......|       :...|||......::     ....|:||:..|..|:.
Worm    63 GKIRIVKNKNIEIIDYHNSENVPSNEQSASAFKFFWDNEIVNNPITGAMAPMFILYNEFKPMCDR 127

  Fly   120 TLRSEALQQ-ILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPS 183
            .|..:.|.| ||  ..:||..:.|.|:. |.:.:...|:..::.:.|.:........:|.|.:.:
Worm   128 ILTDKELHQWIL--SNKFDGYVAESFDF-CSLYLGDHLKLNLLPMFSTIKNVPGSHAIGEPSLLN 189

  Fly   184 HIPALFMAQSQHMNFGGRLANW--------FST--HALNWMYKLLSVPAADAMVQYKFGHDVPSV 238
            :.|:|:      .|||.....|        |::  :|.:.:::.....|.|.:     ..||.:.
Worm   190 YAPSLY------TNFGSDQTVWDRIQDITAFTSFHYAFSNLFERQYRQAYDLL-----NGDVRTW 243

  Fly   239 GELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADL------QRILDNAEEGVIL 297
            .|:::..:.||.|.:..:.....|....:|:||..|..    |.||      .::|| ..:..:|
Worm   244 REILQTATYFFYNNNPYIGFAMPTLEKSVEIGGFTIDP----PHDLSLNEEFDKLLD-LRKSTVL 303

  Fly   298 ISWGSMIRANSLSAAKRDGIIRAVARLKQKV-IWKWE------NETLPNQPPNMHIMKWLPQRDI 355
            ||:|:::::..:....:.|:|:..|:|.... |||:|      ::||..   |:.:.||:||..:
Worm   304 ISFGTVVQSADMPENFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSE---NVFLKKWIPQPAL 365

  Fly   356 LCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTIL-------NFEDI 413
            |..|.:.:|::||||..|.|.||.|.|.:..|::|||.:| |.::.|..|.|.       |:|.:
Worm   366 LADPRLNLFITHGGLGSTLEVAYAGKPSLMIPIFGDQMLN-AKMLSRHGGAISYDKYELENYEKL 429

  Fly   414 GENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRF 478
            .| ||..|:.   :|:::..|.:::...|::|.......:...|..|..|....|:|.:|..:..
Worm   430 TE-TVKEAIS---NKEYNKKALLLAEILHNQPIDPKQNLLKHAEFTAKFGRVHALEPYSVHYNFI 490

  Fly   479 VYYSLDVYAVLALVLGSII 497
            .||.||.||::.:...||:
Worm   491 KYYMLDAYAIIIIFFLSIL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	122/507 (24%)
ugt-2	NP_505672.2	egt	15..498	CDD:223071	125/517 (24%)
ugt-2	NP_505672.2	UDPGT	31..530	CDD:278624	123/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740