DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-49

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_505666.2	Gene:	ugt-49 / 179446	WormBaseID:	WBGene00007070	Length:	525	Species:	Caenorhabditis elegans

Alignment Length:	566	Identity:	163/566 - (28%)
Similarity:	250/566 - (44%)	Gaps:	101/566 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFH--PIMKGLAEAGHDVSVVSHFPDKHPV 71
            |||.|:|...|     ||.:.|..    |.:|..|...  .|...|.:||||  ||....:..|:
Worm     5 LFLLLSLLAVD-----AGKILVYS----PSISRSHLISNGRIADALVDAGHD--VVMFITEYEPL 58

  Fly    72 AHYKDFPLTGMDK-----------------------LTNSVDLKFFEKRTFYSHFQEFFLLYDWG 113
            ..:     ||..|                       |.:|..|.|.|:..|
Worm    59 TEF-----TGTKKAKVITMKGFSTKFAEDMDGIGEYLLSSSRLSFLERLMF-------------- 104

  Fly   114 KQTC-----NLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAP-VIALSSCVMMPWH 172
            ::||     :|..|.|.|:|:  |...|||...||.:. |.:|:...|... .:.:|:..:|...
Worm   105 EKTCTGACDDLMTRREELEQL--RAYNFDVAFSEQIDL-CGVGIVRYLGIKNHLWISTTPIMDAV 166

  Fly   173 YERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSV----PAADAMVQY--KF 231
            ...:|.|...|::|.:     :..:.|.::..|..|  .|...|:.|:    ...|...:.  |:
Worm   167 SYNLGIPAPSSYVPTI-----EENDNGDKMDFWQRT--FNLYMKIGSILIHRYGTDGTTEVFRKY 224

  Fly   232 GHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQK-SKPLPADLQRILDNAEEGV 295
            ..|.|:|.|:..|:|:.|||....|..|:.|....|.:||:.|.| ||||......|:...:|||
Worm   225 IPDFPNVREIAANSSLCFVNSDEVLDLPRPTITKAIYVGGLGIPKVSKPLDKKFTNIMSKGKEGV 289

  Fly   296 ILISWGSMIRANSLSAAKRDGIIRAVARLKQK----VIWKWENET--LPNQPPNMHIMKWLPQRD 354
            ::||.||:|....|.||.::|::||:..:...    .|.|.:|.|  |.....|:.:.:||||.|
Worm   290 VIISLGSIIPFGDLPAAAKEGVLRAIQEISDYHFLIKIAKGDNNTKKLVEGIKNVDVAEWLPQVD 354

  Fly   355 ILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIG----E 415
            ||.||.:|:|:.|||:.|..|.|...||.|..|::.|||.|...:.:||:|.:|...|||    :
Worm   355 ILSHPRLKLFVMHGGINGLVETAIQAVPTVIVPVFADQFRNGRMVEKRGIGKVLLKLDIGYESFK 419

  Fly   416 NTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSR--- 477
            |||:..|.....||  :|.: :......:|.........|.:.....|   :|:...||.||
Worm   420 NTVLTVLNTPSYKK--NAIR-IGKMMRDKPFSPEERLTKWTQFAIDHG---VLEELHVEGSRLNT 478

  Fly   478 FVYYSLDVYAVLALVLGSIIASWVWLLR-LCC---GSSAAQKTKKD 519
            .:||:|||.|.:..|..:::..:::..: |||   ..|..:|:||:
Worm   479 IIYYNLDVIAFVLFVFVAVLHVFIYAFKFLCCKKRSQSNIKKSKKN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	144/511 (28%)
ugt-49	NP_505666.2	UDPGT	17..523	CDD:278624	154/546 (28%)
ugt-49	NP_505666.2	egt	<162..464	CDD:223071	96/311 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14680
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810