DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt-44

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_501933.1	Gene:	ugt-44 / 177939	WormBaseID:	WBGene00008486	Length:	542	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	135/549 - (24%)
Similarity:	224/549 - (40%)	Gaps:	107/549 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVV-----SHFP 66
            |||.:.:..||....:|.  |.|||...|..|.||..|...|...|.:.|::|:::     ....
Worm     7 ALLLIIVYYSQTINGIER--PKKVLVFMPISGHSHLKFMGTIANILQDEGYNVTLLLPILDEGLR 69

  Fly    67 DKHP-VAHYKDFPLTGMDK-------------------LTNSVDLKFFEKRTFYSHFQEFFLLYD 111
            |..| |...|:..|....:                   :.||..:.|.:..|..::.
Worm    70 DTTPLVRKIKNRILVEQSEELIEANAQFRAGGGRENTWVMNSGIIGFLKLGTKVANI-------- 126

  Fly   112 WGKQTCNLTLRSEALQQILRRPGRFDVIIME-----------------QFNTDCMMG-----VAH 154
             .|.:|....::|.|...| |..||||.|.|                 ..:||..:|     :||
Worm   127 -CKASCKNVFQNEDLINYL-RDQRFDVAISEPLYTCGFALFDHLGIETTISTDSHLGLEVSKIAH 189

  Fly   155 QLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMY--KL 217
                                  ||.:..|::||:|.:.|:.|...||..|:..:: .|:.:  |:
Worm   190 ----------------------GASISTSYLPAVFSSGSERMTLIGRAKNYVESY-FNYYFNSKI 231

  Fly   218 LSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHI--QKSKPL 280
            .....|.....||.|   ....||.:..:..|||.:..:..|.......||:|||..  .|.:.|
Worm   232 YENELAGIEGIYKNG---KGWRELSRKNAYMFVNSNPQMDIPSPRTSKFIEIGGISSGPVKQERL 293

  Fly   281 PADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKV-IWKWENETLP------ 338
            |.:..|:|...::.| |||:|:..::..:|...::.:|:....:.... |||:||.|:.
Worm   294 PEEYDRVLSLRKKNV-LISFGTNAKSMFMSDDMKESLIKTFESMPDTTFIWKYENTTVDIVKQYN 357

  Fly   339 NQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERG 403
            .:..|:.:..|:||..:|..|.:.:|::||||..|:|.|:.|.|.:..|::|||..|...|....
Worm   358 KRINNVMLTDWMPQTALLADPRLTLFVTHGGLGSTNEVAFSGKPSIMVPVFGDQTRNARMLERHE 422

  Fly   404 MGTIL------NFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHT 462
            :..:|      ||:.: ..|:.:.|.   ||.:...|:.::....::|:......|.:...||..
Worm   423 VALVLTKYDLTNFKKV-RGTIRKMLN---DKSYSMKAEKLAQMLRNQPESPKEIFIKYFNFVARF 483

  Fly   463 GGAPLLKPSAVEMSRFVYYSLDVYAVLAL 491
            |....|...|.|||...:|.:|..|:|::
Worm   484 GKPHGLDSYAAEMSFIEFYYIDFMAILSI 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	126/524 (24%)
ugt-44	NP_501933.1	UDPGT	27..510	CDD:278624	127/523 (24%)
ugt-44	NP_501933.1	egt	<250..519	CDD:223071	73/268 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161407
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790