DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36D1 and ugt-24

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_500931.3	Gene:	ugt-24 / 177380	WormBaseID:	WBGene00016762	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	537	Identity:	129/537 - (24%)
Similarity:	221/537 - (41%)	Gaps:	59/537 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ELVEAAGPLKVL---GLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTG 81
            :|:.||.|.|:|   .|:.|   ||....:.:...|.:|||:|::.      .|:........:.
Worm    12 KLLNAALPYKILIYSNLYGH---SHIKVLNTVADTLTDAGHNVTIF------RPIIESSQLDKSS 67

  Fly    82 MDKLTNSV----DLKFFEKRTFYSHFQEFFLLYD-----------------WGKQTCNLTLRSEA 125
            : |..|.:    |.:..||.:....|......:|                 :|.| |...:|.:.
Worm    68 V-KTKNVIYIEPDEEVVEKMSKIDQFSGSLWTFDSTHPSAMIAKSNALVGFFGTQ-CKKVMRQQK 130

  Fly   126 LQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQ-APVIALSSCVMMPWHYERMGAPLIPSHIPALF 189
            :...| |...||:.|.|..: .|...:...|: ...:.:.|||......:.:|.|:.||::|...
Worm   131 ILDQL-RDENFDLAITEPVD-GCAYAIFEYLKIRDHVTVLSCVRFDHVSDILGQPIAPSYVPGTQ 193

  Fly   190 MAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQ-YKFGHDVPSV----GELVKNTSMFF 249
            ...:..|....||.|:...:...:.:       |:.:.| |:...|:..:    .|::...|..|
Worm   194 SFFNDRMTMKERLLNFIQFYYGRFTF-------ANILDQEYEMAKDILGIQRSWREVLPEASFIF 251

  Fly   250 VNQHYSLSGPKVTPPNVIELGGIHI---QKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSA 311
            .|....|..|..|...:|.:||..:   :||..:......|| |..:..:|||:||..::..:..
Worm   252 SNHIPVLDFPSPTFDKIIPIGGFTVKTNEKSLKIDKKWDAIL-NIRKKNVLISFGSNAKSKDMPE 315

  Fly   312 AKRDGIIRAVARLKQKV-IWKWE--NETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGT 373
            ..:..::|..:.:.... |||:|  |..:.....|:.|..||||.::|....|.||::||||...
Worm   316 EYKKTLLRVFSSMPDTTFIWKYEDPNVNIAKNLDNVFISSWLPQNELLADSRVTVFVTHGGLASV 380

  Fly   374 SEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMR-ALKKALDKKFHDA-AKV 436
            .|.|..|.|.:..|::.||..|...|...|...:|...|:....::| .|...|.|..:.. ||.
Worm   381 MELALMGKPAIMIPIFADQGRNAQMLKRHGGAAVLQKTDLSNFDLVRDTLNDVLTKPSYKLNAKK 445

  Fly   437 VSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWV 501
            ::...:::|..|....:..||..|..|..|:|.......:...||.:|:..::..||.|:...:|
Worm   446 LAEMLNNQPTNAKEVLVKHVEFAARFGKLPMLDNYGRHQNIVEYYFIDILTIILSVLISVFYIFV 510

  Fly   502 WLLRLCCGSSAAQKTKK 518
            .|||.....:.:.|.|:
Worm   511 RLLRFMLSRNRSTKDKR 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	118/498 (24%)
ugt-24	NP_500931.3	UDPGT	32..519	CDD:278624	119/504 (24%)
ugt-24	NP_500931.3	egt	<251..504	CDD:223071	69/253 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860