Protein Alignment Ugt36D1 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_001246082.2
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 134/511 - (26%)
• Similarity: 246/511 - (48%)
• Gaps: 51/511 - (9%)

  Fly    40 SHFHFFHPIMKGLAEAGHDVSVVSHF------PDKHPVAHYKDFP--LTG-------MDKLTNSV 89
            ||:.....|:|.|.:.||:|:|::..      |:......::.:|  ||.       |.::....
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWS 98

  Fly    90 DLKFFEKRTFYSHFQE----FFLLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMM 150
            |::   |.:|:.:|.:    .:.|||..:..|...:.::.:.:.|:. .|||::.     .|.:.
Human    99 DIR---KDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQE-SRFDIVF-----ADAVF 154

  Fly   151 GVAHQLQA--PVIALSSCVMMP-WHYERMGAPLI--PSHIPALFMAQSQHMNFGGRLANWFSTHA 210
            .....|.|  .:..:.|....| :..||....||  ||:||.:....|..|.|..|:.|......
Human   155 PCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLY 219

  Fly   211 LNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQ 275
            .::.:::..:...|.......|... ::.|.:....::.:...:|...|....|||..:||.|.:
Human   220 FDFWFQMSDMKKWDQFYSEVLGRPT-TLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCK 283

  Fly   276 KSKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPN 339
            .:||||.:::..:.:: |.||::.|.||:|  ::::|.:.:.|..|:|::.|||:|:::.    |
Human   284 PAKPLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIPQKVLWRFDG----N 342

  Fly   340 QPP----NMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALV 400
            :|.    |..:.||:||.|:|.||..:.|::|||..|..||.|.|:|:|..|::.||..|.|.:.
Human   343 KPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMK 407

  Fly   401 ERGMGTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGG 464
            .:|....|:|..:....::.|||..: |..:.:....:|...|.:|.:.|..|::|:|.|....|
Human   408 AKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKG 472

  Fly   465 APLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLC--CGSSAAQKTKK 518
            |..|:.:|.:::.|.|:||||...|...:.::|   ..:.:.|  |....|:|.||
Human   473 AKHLRVAAHDLTWFQYHSLDVIGFLLACVATVI---FIITKFCLFCFWKFARKGKK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	122/471 (26%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	132/509 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740