DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and Ugt3a1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_997099.2	Gene:	Ugt3a1 / 105887	MGIID:	2146055	Length:	523	Species:	Mus musculus

Alignment Length:	547	Identity:	136/547 - (24%)
Similarity:	251/547 - (45%)	Gaps:	92/547 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSH----FPD------KHPVAHYK 75
            |:|||..|.:..|    ..||:...:.:.:.|...||||..:.:    .||      .:.|.:::
Mouse    19 LLEAAKILTISTL----SASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENSSYQVINWR 79

  Fly    76 DFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGK--------------QTCNLTLRSEAL 126
                           |...:::||.:.:......|.:|:              ..|:..|..:.:
Mouse    80 ---------------LPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQYFADLCSHLLSRKDI 129

  Fly   127 QQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERM--GAPLIP-SHIPAL 188
            .::|::. .||:::::..:. |...:..:|....::     .:|:.:..|  |.|..| |:.|..
Mouse   130 MELLQKE-NFDLVLLDSMDL-CSFLIVEKLGKRFVS-----FLPFQFSYMDFGLPNAPLSYAPVY 187

  Fly   189 FMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDV---------PSVGELVKN 244
            ....:..|:|.||:.|..       |:...:....|...||  |:.|         |.:.:|:..
Mouse   188 GSGLTDQMDFWGRVKNIL-------MFFHFTKKRRDIFSQY--GNTVQEHFAEGSQPVLSDLLLK 243

  Fly   245 TSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDN-AEEGVILISWGSMIRANS 308
            ..::|||..::|...:...||.:.:||:..:..:|:|.||:..:.. .:.|.:|::.||::   |
Mouse   244 AELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLEDFISQFGDSGFVLVALGSVV---S 305

  Fly   309 LSAAKRDGIIR----AVARLKQKVIWKWENETLPNQ---PPNMHIMKWLPQRDILCHPNVKVFMS 366
            :..:|.  ||:    |.|.|.|.|:|..::...|..   .||:.||.||||.|:|.||::::|::
Mouse   306 MIQSKE--IIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAPNVKIMDWLPQIDLLAHPSIRLFVT 368

  Fly   367 HGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL-DKKF 430
            |||:....||.:.|||:|..|.:|||..|...:..:.:|..:..:.:...:.:..:|:.: |:::
Mouse   369 HGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKEVIEDQRY 433

  Fly   431 HDAA---KVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYA-VLAL 491
            ..||   ||:..|....|.|.|   :.|::|:..||||..|||.|.:......|.|||:. :|.|
Mouse   434 KTAAMASKVIRQSHPLTPAQRL---VGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFLLGL 495

  Fly   492 VLGSIIASWVWLLRLCCGSSAAQKTKK 518
            .||::..|...|:.:....|.::|.|:
Mouse   496 TLGTLWLSVKVLVAVTRYLSISRKVKQ 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	123/508 (24%)
Ugt3a1	NP_997099.2	UDPGT	24..488	CDD:278624	121/506 (24%)
Ugt3a1	NP_997099.2	egt	<235..488	CDD:223071	79/260 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740