DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36D1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	535	Identity:	150/535 - (28%)
Similarity:	248/535 - (46%)	Gaps:	75/535 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVS-----HFPDKHPVAHYKD----FPLTGMDK 84
            |:| :|||.| ||:...:.:::.|...||.:||:.     :.|:..|  ||..    |.|.|.|:
Zfish    53 KIL-VFPHEG-SHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSP--HYDSINVPFLLGGDDQ 113

  Fly    85 LTNS------------------VDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTL-----RSEAL 126
            ..:|                  :|::..||      |.|..      ::.|.:.:     ....:
Zfish   114 FYHSFIFRQLQIRREQRWTRFKLDMELKEK------FSEMH------RKICEMVIHIVEKEPAIM 166

  Fly   127 QQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPW------HYERMGAPLIPSHI 185
            :||  :...||:::.:..|...:: :||.|..|::     ..:.|      |:..  ||..||::
Zfish   167 KQI--KEANFDIMLTDPANGGGVV-LAHYLHLPLV-----FNVQWTVHGEAHFAI--APSPPSYV 221

  Fly   186 PALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVG--ELVKNTSMF 248
            |......:..|:|..|:.|...:....::|:....|...|:....||   |.:.  ||.:...::
Zfish   222 PFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALCNRLFG---PGLDYFELFQAADIW 283

  Fly   249 FVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAA 312
            .:...:....|:.|.||||.:||.|...:|.||.||:..|.:: |.|||::|.|:::....:..|
Zfish   284 LMRADFVFDFPRPTMPNVIYIGGFHCSPAKALPKDLEDFLQSSGEHGVIVMSLGTLVAQLPMDIA 348

  Fly   313 KRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAA 377
              |.|:.|.|.|.|||||::..:...|...|..::.||||.|:|.||..:||:||||..|..||.
Zfish   349 --DEIVAAFAELPQKVIWRYTGDRPANVGNNTLLVNWLPQNDLLGHPKTRVFVSHGGTNGVFEAI 411

  Fly   378 YCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKAL-DKKFHDAAKVVSHSF 441
            |.|||:|..|:..||..|...:..:|:..:|:...|..|....||::.| |..:....:.:|...
Zfish   412 YHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDALQEVLNDPSYRSNMQKLSSLH 476

  Fly   442 HHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLR- 505
            ...|.:.|.:|::|.|.|....||..|:..:.:|..:.|:|:||...|..||..|:.....::|
Zfish   477 KDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVDVGVFLVSVLCFIVFLMFKIVRC 541

  Fly   506 LCCGSSA-AQKTKKD 519
            |||...| ..:.|:|
Zfish   542 LCCRFCAKTNRAKQD 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	136/494 (28%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740