Protein Alignment Ugt36D1 and ugt2a1

DIOPT Version :10

• Sequence 1: NP_609910.1
• Gene: Ugt36D1 / 35138
• FlyBaseID: FBgn0032713
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001177979.1
• Gene: ugt2a1 / 100006320
• ZFINID: ZDB-GENE-080721-20
• Length: 539
• Species: Danio rerio
• Alignment Length: 570
• Identity: 159/570 - (27%)
• Similarity: 268/570 - (47%)
• Gaps: 90/570 - (15%)

  Fly     3 SPRVAL-LFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFP 66
            |||.:. :||.|||.....|:..:|. |:| ::| ...||:.....|:..|.|.||:::||:|..
Zfish     2 SPRGSTGVFLLLALLLNQNLLCVSGG-KIL-VWP-AEFSHWLNIKVILDVLIERGHNITVVTHTA 63

  Fly    67 ----DKHPVAHYK----DFPLTGMDKLTN------------------SVDLKFFEKRTFYSHFQE 105
                ...|.|.|.    ..|.|..:.:.|                  :..||..|..|..:
Zfish    64 TPSVQTTPSAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTAT---- 124

  Fly   106 FFLLYDWGKQTCN-LTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVI-------- 161
                 ...|.||| |..|::.|::  .:..:||||:.:.... |...:|.:|..|:|
Zfish   125 -----AQNKITCNALFSRADLLEK--WKMEKFDVILADPLYI-CGEILAQKLDIPLIFSLRFTFG 181

  Fly   162 -ALSS-CVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAAD 224
             .|.. |..||       ||  ||::||:...::..|:|..||.|:......::::.|::
Zfish   182 NTLERLCGQMP-------AP--PSYVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVT----- 232

  Fly   225 AMVQYKFGHDVPSVGELVKNTSM---------FFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPL 280
               ::|:.|....|  |.|.|:|         :.:..::....|:..|||...:||:|.:.:|||
Zfish   233 ---KFKWDHYYSEV--LGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPL 292

  Fly   281 PADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNM 344
            ..:::..:.:: :.||::.|.||||:  :|::.:.:.|..|:.::.|||:|::..:|.....||.
Zfish   293 SKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNT 355

  Fly   345 HIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILN 409
            .|..|:||.|:|.||..|.|::|||..|..||.|.|||:|..|::.||..|...:..:|...:|:
Zfish   356 KIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLD 420

  Fly   410 FEDIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAV 473
            ...:....::.|||..|:. .:.::...:|...|.:|.:.|..|::|:|.|....||..|:..|.
Zfish   421 INTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAH 485

  Fly   474 EMSRFVYYSLDVYAVLALVLGSIIASWV----WLLRLCCGSSAAQ-KTKK 518
            |:|.:.|:.|||.|.|..:...|...||    :|.|.|...:..: ||:|
Zfish   486 ELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERKTQK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36D1	NP_609910.1	GT1_Gtf-like	28..457	CDD:340817	126/476 (26%)
ugt2a1	NP_001177979.1	UDPGT	27..526	CDD:278624	146/534 (27%)