Protein Alignment Ugt36F1 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 144/529 - (27%)
• Similarity: 236/529 - (44%)
• Gaps: 107/529 - (20%)

  Fly    33 SHFDFFRPMFLALAERGHNISMYS--------------------YFPLEKPVAN--YTDYVFQGM 75
            ||:...:.:...|..|||.:::.:                    :.|.::...|  :.|.....:
Human    34 SHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVL 98

  Fly    76 PLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLR-SCKVALNSPLITQLLKSPIR---YDVI 136
            |.|          |.|:.:   .|:..:|:    .:| :.|:...|.:..|.|...::   |||:
Human    99 PGL----------STWQSV---IKLNDFFV----EIRGTLKMMCESFIYNQTLMKKLQETNYDVM 146

  Fly   137 LLEHFSNDCMAAVAHLLNAP-VIAL---------SSCAIMPWHYKRMGSPFINPIMPMNFLP--- 188
            |::... .|...:|.||..| |:.|         .||..:|              .|::::|
Human   147 LIDPVI-PCGDLMAELLAVPFVLTLRISVGGNMERSCGKLP--------------APLSYVPVPM 196

  Fly   189 --YTDEMSLIDRLNN-----FFHFHTVNTLYNMITQPATDALIAERFGPGLP-PINEIVKNTSLM 245
              .||.|:.::|:.|     .|||...:..|:...:..:.||       |.| .:.|.|....:.
Human   197 TGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKAL-------GRPTTLCETVGKAEIW 254

  Fly   246 LINQHYALTGPRPYAPNVIEVGGLQVGPIKPLP------QHLLDLLDRS-PNGVIYISWGSMVNS 303
            ||..::....|:||.||...||||...|.|.||      |.:.:.:..| .:|::..|.||:..:
Human   255 LIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKINFYLQEMENFVQSSGEDGIVVFSLGSLFQN 319

  Fly   304 NTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAF 364
            .|  ..|.:.:..:::|:.:       |.|...:.|:||    |...:||:||.|||.|||.:||
Human   320 VT--EEKANIIASALAQIPQ-------KVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAF 375

  Fly   365 ISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDK 428
            |:|||:.|..|||:.||||:..|.:|||..|...:|.:|..|.::|:...|..:.|.|| :|.|.
Human   376 ITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDS 440

  Fly   429 KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGIL 493
            .:.|...|.|.....:|:.|:..|.:|||.|:::.||.|::|.|..:.|..:.||||:.|.|..:
Human   441 SYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACV 505

  Fly   494 FLLIVALRK 502
            ...|....|
Human   506 ATAIFLFTK 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	140/512 (27%)
		YjiC	38..461	CDD:224732	128/481 (27%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	144/529 (27%)
		egt	<267..498	CDD:223071	85/239 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740