DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt5b4

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001074161.1	Gene:	ugt5b4 / 791210	ZFINID:	ZDB-GENE-070112-2332	Length:	531	Species:	Danio rerio

Alignment Length:	560	Identity:	153/560 - (27%)
Similarity:	259/560 - (46%)	Gaps:	74/560 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNIS---MYSYFPLEKPV 64
            |.|:.|...|:.....::.::| :|...| ||:.....:..||..:||||:   |...:.:::..
Zfish     9 LWPVTLCLLLVMAPVVESGNVL-VFPVDG-SHWVNMNILVEALHAKGHNITVIRMSDSWYIKEFS 71

  Fly    65 ANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHD---WGLRSCKVAL-------- 118
            .:||....:.....::.: |..|.|.           ...:|.|   ||....::.:
Zfish    72 PHYTSITLKSSGGFSEDI-LETFASR-----------LITILRDGSTWGRLKLEMEMWQSSLKIM 124

  Fly   119 ------------NSPLITQLLKSPIRYDVILLEHFSNDCM---AAVAHLLNAPVIALSSCAIM-P 167
                        :..||..|.|:  :||:.|    ::..|   ..:.:.|..|::.....||. .
Zfish   125 ETEREMIINMIEDQQLIDSLKKT--KYDLFL----TDPAMYGGVILGNYLKLPIVYNVRWAIFGE 183

  Fly   168 WHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERF-GPG 231
            .|:....||.  ..:|:..|...|.||.::|:.|...:....|....:..| |..::.||| |||
Zfish   184 GHFVIAPSPL--SYVPVAMLELPDRMSFLERVKNVVMYIITETQIAFLIAP-TYNVLCERFIGPG 245

  Fly   232 LPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYI 295
            :...| :|:...|.|....:....|||..||::.:.|.|..|.||||:.|.|.:..| .:|||.:
Zfish   246 VNLFN-LVQGADLWLHRADFVFEYPRPTMPNIVYMAGFQCKPSKPLPKDLEDFVQSSGDHGVIVM 309

  Fly   296 SWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPS----NLYTFDWLPQRDLL 356
            |.|:::..  ||.....|:.::.::|.: ..:.|:|.      |:||    |....||:||.|||
Zfish   310 SLGTIIGQ--LPDDVAEAIAEAFAELPQ-KIIWRYKG------KRPSALGNNTLIMDWMPQNDLL 365

  Fly   357 CHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRG 421
            .|||.|||::|||..|..|||:.|||::......||..|...::.||....|||...|.....:.
Zfish   366 GHPKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMDKESFLKT 430

  Fly   422 LR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDV 485
            :: ::.|..:.|.::|.|...:..|:.|:..|.:|||.|:::.||.|:::|:..:.|..|:|:||
Zfish   431 VKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDV 495

  Fly   486 LLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            :|..:..:.|:|:::..:|:.|....|    .|.||.|.|
Zfish   496 ILVLISAVSLIILSIYAVIRYFCCKIC----MRKTKIKRQ 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/504 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	124/459 (27%)
ugt5b4	NP_001074161.1	egt	12..501	CDD:223071	141/521 (27%)
ugt5b4	NP_001074161.1	UDPGT	27..531	CDD:278624	148/540 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740