Protein Alignment Ugt36F1 and UGT2B17

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 147/527 - (27%)
• Similarity: 245/527 - (46%)
• Gaps: 69/527 - (13%)

  Fly    33 SHFDFFRPMFLALAERGH-------------NISMYSYFPLEKPVANYT-----DYVFQGMPLLT 79
            ||:...:.:...|.:|||             |.|..|...||....:.|     |:..:.....|
Human    34 SHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWT 98

  Fly    80 DIVDLSNFESEWKPLGLPFKVPTYFM--------LHDWGLRSCKVA-LNSPLITQLLKSPIRYDV 135
            ..:..:.|   |          :||.        ..|:.::.|:.| ||..|:.:|.:|  ::||
Human    99 YSISKNTF---W----------SYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQES--KFDV 148

  Fly   136 ILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINP--IMPMNFLPYTDEMSLIDR 198
            :|.:.. |.|...:|.|||.|.: .|....:.:..::.|..|:.|  .:|:.....:|:|..::|
Human   149 LLADAV-NPCGELLAELLNIPFL-YSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSDQMIFMER 211

  Fly   199 LNNFFHFHTVNTLYNMITQPATDALIAERFG-PGLPPINEIVKNTSLMLINQHYALTGPRPYAPN 262
            :.|..:....:..:........|...:|..| |  ..:.|.:....:.||..::....|||:.||
Human   212 IKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRP--TTLFETMGKAEMWLIRTYWDFEFPRPFLPN 274

  Fly   263 VIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNF 326
            |..||||...|.||||:.:.:.:..| .||::..|.|||:::.:..|....|  .:::|:.:
Human   275 VDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIA--SALAQIPQ--- 334

  Fly   327 VMRWKSLESLEDKQP----SNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTP 387
                |.|...:.|:|    ||...:.||||.|||.|||.:|||:|||..|..|||:.|:||:..|
Human   335 ----KVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIP 395

  Fly   388 FYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKL 451
            .:.||..|...:|.:|..:.||.|...|..:...|: :|.|..:.|.:.:.|.....:|:.|:..
Human   396 LFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDR 460

  Fly   452 ATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKI 516
            |.:|||.|:::.||.|::..|.::.||.|:|:||:.|.|..:..:|..:.|.     ..||..|:
Human   461 AVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKC-----CLFCFRKL 520

  Fly   517 SRDTKTK 523
            ::..|.|
Human   521 AKTGKKK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/489 (28%)
		YjiC	38..461	CDD:224732	126/458 (28%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	144/516 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740