Protein Alignment Ugt36F1 and UGT2B10

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001066.1
• Gene: UGT2B10 / 7365
• HGNCID: 12544
• Length: 528
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 134/507 - (26%)
• Similarity: 238/507 - (46%)
• Gaps: 58/507 - (11%)

  Fly    45 LAERGHNISMYS------------------YFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEW 91
            |.:|||.:::.:                  .:|.......:.:.:.|.:..|::|    ..::.|
Human    45 LVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEI----QKDTFW 105

  Fly    92 KPLGLPFKVPTYFMLHDWGLRS-----CK-VALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVA 150
                |||......:   |.:..     || |..|..|:.:|.:|  |:|::..:.:. .|...:|
Human   106 ----LPFSQEQEIL---WAINDIIRNFCKDVVSNKKLMKKLQES--RFDIVFADAYL-PCGELLA 160

  Fly   151 HLLNAPVIALSSCAIMP-WHYKRMGSPFINP--IMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLY 212
            .|.|.|.:  .|.:..| :.::|....||.|  .:|:.....:|:|:.::|:.|..:....:..:
Human   161 ELFNIPFV--YSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWF 223

  Fly   213 NMITQPATDALIAERFG-PGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKP 276
            .:......|...:|..| |  ..::|.::...:.|:...:....|.|:.|||..||||...|.||
Human   224 QIFNMKKWDQFYSEVLGRP--TTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKP 286

  Fly   277 LPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQ 340
            ||:.:.:.:..| .|||:..|.||||::.|  ..:.:.:..:::::.:   .:.|:...:..|..
Human   287 LPKEMEEFVQSSGENGVVVFSLGSMVSNMT--EERANVIATALAKIPQ---KVLWRFDGNKPDAL 346

  Fly   341 PSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFG 405
            ..|...:.|:||.|||.|||.||||:|||..|..|||:.|:||:..|.:.||..|...:|.:|..
Human   347 GLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAA 411

  Fly   406 VIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQ 469
            |.|||....|..:...|: :|.|..:.|.:.:.|.....:|:.|:..|.:|||.|:::.||.|::
Human   412 VRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLR 476

  Fly   470 SEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTK 521
            ..|.::.|..|:|:||:.|.|..:..::..:.|.     ..||..|.:|..|
Human   477 VAAHNLTWFQYHSLDVIGFLLACVATVLFIITKC-----CLFCFWKFARKGK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	126/471 (27%)
		YjiC	38..461	CDD:224732	117/445 (26%)
UGT2B10	NP_001066.1	UDPGT	23..524	CDD:278624	134/507 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150142
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740