Protein Alignment Ugt36F1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 515
• Identity: 141/515 - (27%)
• Similarity: 237/515 - (46%)
• Gaps: 50/515 - (9%)

  Fly    33 SHFDFFRPMFLALAERGHNISMYS------------------YFPLEKPVANYTDYVFQGMPLLT 79
            ||:...:.:...|.:|||.:::.:                  .:|.........:::.|.:...:
Human    34 SHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWS 98

  Fly    80 DIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCK-VALNSPLITQLLKSPIRYDVILLEHFSN 143
            |:..    ::.|.......::.:.|  .|...:.|| |..|...:.::.:|  |:|||..:...
Human    99 DLPK----DTFWLYFSQVQEIMSIF--GDITRKFCKDVVSNKKFMKKVQES--RFDVIFADAIF- 154

  Fly   144 DCMAAVAHLLNAPVIALSSCAIMP-WHYKRMGSPFINP--IMPMNFLPYTDEMSLIDRLNNFFHF 205
            .|...:|.|.|.|.:  .|.:..| :.:::....||.|  .:|:.....||:|:.::|:.|..:.
Human   155 PCSELLAELFNIPFV--YSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYV 217

  Fly   206 HTVNTLYNMITQPATDALIAERFG-PGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGL 269
            ...:..:.:......|...:|..| |  ..::|.:....:.||...:....|.|..|||..||||
Human   218 LYFDFWFEIFDMKKWDQFYSEVLGRP--TTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGL 280

  Fly   270 QVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSL 333
            ...|.||||:.:.|.:..| .|||:..|.||||::.|  ..:.:.:..:::|:.:   .:.|:..
Human   281 HCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMT--EERANVIASALAQIPQ---KVLWRFD 340

  Fly   334 ESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGA 398
            .:..|....|...:.|:||.|||.|||.||||:|||..|..|||:.|:||:..|.:.||..|...
Human   341 GNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAH 405

  Fly   399 VKQRGFGVIVDFRDFDSNHITRGL-RIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKY 462
            :|.||..|.|||....|..:...| |:|.|..:.|.|.:.|.....:|:.|:..|.:|||.|:::
Human   406 MKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRH 470

  Fly   463 GGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTA-FCRGKISRDTK 521
            .||.|::..|..:.|..|:|:||      |.|||:.....:..:.|.. ||..|.:|..|
Human   471 KGAKHLRVAAHDLTWFQYHSLDV------IGFLLVCVATVIFIVTKCCLFCFWKFARKAK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	131/478 (27%)
		YjiC	38..461	CDD:224732	120/447 (27%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	141/515 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150132
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740