Protein Alignment Ugt36F1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 151/559 - (27%)
• Similarity: 252/559 - (45%)
• Gaps: 78/559 - (13%)

  Fly     6 LALLAFLLRPKP-NDAAHILGLFQHPGKSHFDFFRPMFLALAERGH-----------NISMYSYF 58
            ||.|..||...| .:...:| :|...| ||:...|.:...|..|||           :|....:|
  Rat    10 LAGLLLLLYALPWAEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFF 72

  Fly    59 PLEKPVANYTDYVF--QGMPLLTDIVDLSNFESEWKPLGLPFK-VPTYFMLHDWGLRSCKVALNS 120
            .|:.....||...|  |.|..:..:.:..|:...:.......| :.|..      ||||...|::
  Rat    73 TLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVL------LRSCMNLLHN 131

  Fly   121 PLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVI---ALSSCAIMPWHYKRMGSPFINPIM 182
            ..:.|.|.|. .:|::|.:... .|.|.:|..|..|.:   ....|.|        .|.......
  Rat   132 GSLLQHLNSS-SFDMVLTDPVI-PCGAVLAKYLGIPTVFFLRYIPCGI--------DSEATQCPK 186

  Fly   183 PMNFLP-----YTDEMSLIDRLNNFFH-------FHTVNTLYNMITQPATDALIAERFGPGLPPI 235
            |.:::|     .:|.|:.:.|:.|..:       .|...|.|..:   |::.|..|      ..:
  Rat   187 PSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESL---ASELLQRE------VSL 242

  Fly   236 NEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGS 299
            .|::.:.|:.|....:....|||..||::.:||:.....|||.|.....::.| .:|::..|.||
  Rat   243 VEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGS 307

  Fly   300 MVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAF 364
            ||:.  :|..|...:.:::.::.:   .:.|:...:.......|.....||||.|||.|||.|||
  Rat   308 MVSE--IPEKKAMEIAEALGRIPQ---TVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAF 367

  Fly   365 ISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDK 428
            |:|.|..|..|.|..||||::.|.:|||..|:..::.||.||.::..:..::.:...|: :|.:|
  Rat   368 ITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNK 432

  Fly   429 KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGIL 493
            .:.|.:.|.|...:.|||.|:.||.:|:|:|:::.||||::..|..:.|..|:|:||      |.
  Rat   433 SYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDV------IG 491

  Fly   494 FLLIVALRKLIKIFKTAF--CR------GKISRDTKTKT 524
            |||.:.|..:..::|:..  ||      |::.:..|:||
  Rat   492 FLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKT 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	GT1_Gtf-like	21..448	CDD:340817	117/457 (26%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	142/533 (27%)