DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP005751

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_001688725.1	Gene:	AgaP_AGAP005751 / 5667252	VectorBaseID:	AGAP005751	Length:	519	Species:	Anopheles gambiae

Alignment Length:	522	Identity:	147/522 - (28%)
Similarity:	235/522 - (45%)	Gaps:	55/522 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLL----RPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYS---------- 56
            |.|:..||    |.:.:..|:||.|...|..||..:.|....|||.||||:::.|
Mosquito     3 LGLVILLLFQQCRWQLSAGANILCLTPVPSPSHHIWNRVWIEALAARGHNLTVLSADVDERTAPP 67

  Fly    57 ---YFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVAL 118
               |..||..   |:|       |.|:: ||....|.....|:.       .|:.||...|:..|
Mosquito    68 NITYIHLEHA---YSD-------LHTEL-DLFQMASHSALTGIK-------DLYVWGTAMCRGVL 114

  Fly   119 NSP--LITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFIN-- 179
            .|.  .:.|......|:|:|:.:.....|:..:.|..:.|.:    ..:..::..:..:.|:.
Mosquito   115 RSKGLQVIQAYPDDFRFDLIIADITCGPCLFPLIHKFHHPPL----IGVTAYNNPQFTADFVGGH 175

  Fly   180 ---PIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLY-NMITQPATDALIAERFG-PGLPPINEIV 239
               ..:|...|.|..:|:...|..|:. .|.|:..| :.:..|..:.::...|. ||:|.:.::.
Mosquito   176 KHYAYVPFFTLNYDSDMTFYQRFYNWV-LHNVDHFYRHHVFLPRIEQMVRNHFRYPGMPSLEQME 239

  Fly   240 KNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSN 304
            .||.|:|.|.||::.......||.|.||||||.|...||..|...:.....|.:..|.|:.|.|.
Mosquito   240 HNTVLLLANFHYSVDFAESIGPNHIPVGGLQVRPANHLPDDLATFIAAGREGSVLFSLGTNVRSA 304

  Fly   305 TLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGG 369
            .|...:.....::..||.||||:.:::.|.|.|  .|:|:....:|||.|:|..|.::|||:|||
Mosquito   305 DLEMERIHMFLEAFRQLPEYNFLWKFEELPSFE--VPANVLIRAFLPQNDVLAQPNVKAFITHGG 367

  Fly   370 LLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAER 433
            :|.|.||...||||:..||..||:.|.......|..:.:.........|...|| |:.:..:.:.
Mosquito   368 MLSTHEATWHGVPMVGIPFICDQYRNLHKSVTAGVALRLAHDSLSVEQIAAALREILTNTSYRDA 432

  Fly   434 VRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIV 498
            ::|.|...|.:|..|:..|.||||.|:::.....|||..:|:.:..|...|:.   |.::.|.::
Mosquito   433 MKRRSALLRDQPEHPLDRAVWWIEWVLRHPDGKAIQSPTKHMRFWQYELYDIK---LALILLTVL 494

  Fly   499 AL 500
            |:
Mosquito   495 AV 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	139/490 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	126/445 (28%)
AgaP_AGAP005751	XP_001688725.1	egt	1..493	CDD:223071	146/517 (28%)
AgaP_AGAP005751	XP_001688725.1	UDPGT	34..500	CDD:278624	137/491 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020