DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP005750

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_001688724.1	Gene:	AgaP_AGAP005750 / 5667251	VectorBaseID:	AGAP005750	Length:	519	Species:	Anopheles gambiae

Alignment Length:	545	Identity:	159/545 - (29%)
Similarity:	258/545 - (47%)	Gaps:	50/545 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYS--------- 56
            :.|:.|..||.|   ....||:||.:...|..||..:.|.:...|..||||:::.|
Mosquito     5 VSLVALCALATL---SAVQAANILCIMTVPSPSHHIWNRVIMEELVARGHNVTVVSQDGDASRTN 66

  Fly    57 --YFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALN 119
              |..|||..:  |.|..:|:    |::::|.        ..||:  :.|...::.|..|:.||.
Mosquito    67 LTYIMLEKVYS--TLYEDEGL----DLLEVSK--------ETPFQ--SLFTFREFYLGMCRGALK 115

  Fly   120 SPLITQLLKSP--IRYDVILLEHFSNDCMAAVAHLLN-APVIALSSCAIMPWHYKRMGSPFINPI 181
            |..:..:|..|  .|:|::|.:.....|:..:.|..| .|::||::.:..|:....:|.......
Mosquito   116 SNGLNVILNYPDSFRFDLVLYDFGCGPCLLPLLHKFNYPPLVALTAFSNPPYSVDIVGGHKHFAY 180

  Fly   182 MPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG-PGLPPINEIVKNTSLM 245
            .|...|||..:||..:|..|.:.......|......|..|.::.|||| ..:|.|.:|.:.|.||
Mosquito   181 TPHYALPYGFDMSFAERAYNTYLCLWDAGLRKFTIMPQLDVMVRERFGFNDMPYIQDIEQRTVLM 245

  Fly   246 LINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGK 310
            |:|.:.:...|.|..||||.:||..:...||||..|.:.:.::..|.:..|.||.:.|:.:...:
Mosquito   246 LVNTNPSFDAPEPLPPNVIAIGGAHIKEPKPLPSDLEEFVGKAKKGAVLFSLGSNIRSDMIGEQR 310

  Fly   311 RSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTE 375
            :....::..|:.:|:|:  ||....|....|.|:....||||..:|.||:.|.||:|.|.|.|.|
Mosquito   311 QRMFIEAFRQMPDYHFL--WKFESKLNLPLPPNVIIRPWLPQNSILNHPRTRGFITHSGGLSTQE 373

  Fly   376 AIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFD--SNHITRG--LRIILDKKFAERVRR 436
            |...|||::..||:.||..|   :|:...|.:.:..||.  |....|.  |:::....:.|.::|
Mosquito   374 ASWFGVPLIGMPFFVDQHRN---LKRSLIGGVAEPLDFGAMSTEKIRATVLKVLETPIYRENMQR 435

  Fly   437 SSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLG-ILFLLIVAL 500
            .:..||.:|..|:..|.||||:|:::....|::|....:.....|.:||..|:.| |||:|.:|
Mosquito   436 RAMYFRDQPEKPLDRAIWWIEYVLRHPTVEHLRSPTLKLGTARSNLLDVYGFFAGVILFVLWLA- 499

  Fly   501 RKLIKIFKTAFCRGKISRDTKTKTQ 525
               :.|.:...|..|:.  .|.|.|
Mosquito   500 ---VFIVRRVCCGRKMK--PKKKQQ 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	141/486 (29%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	129/441 (29%)
AgaP_AGAP005750	XP_001688724.1	egt	1..461	CDD:223071	141/479 (29%)
AgaP_AGAP005750	XP_001688724.1	UDPGT	34..519	CDD:278624	148/511 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020