DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and AgaP_AGAP007589

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_001687884.1	Gene:	AgaP_AGAP007589 / 5667069	VectorBaseID:	AGAP007589	Length:	533	Species:	Anopheles gambiae

Alignment Length:	569	Identity:	167/569 - (29%)
Similarity:	270/569 - (47%)	Gaps:	96/569 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVA 65
            |....:.|||.||.....::|.|:.:|....|||....:.:...||.|||.::|.|.|||:||..
Mosquito    13 MVTFSMGLLATLLVIGHAESAKIVCVFPTASKSHVLGAQALLKELAHRGHEVTMVSAFPLKKPPK 77

  Fly    66 NYTD-YV-------------FQG-----MPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGL 111
            ||.| |:             .||     |.||..|:..|                     ||
Mosquito    78 NYRDVYIPIEDAFSSIMSDFMQGGSRNMMKLLPKILRAS---------------------HD--- 118

  Fly   112 RSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSP 176
             :....|||..:.:|.:.. ::|:.|:..|.|..:..|..|...|.:.         ::..:||.
Mosquito   119 -ASNATLNSAELLRLAREE-QFDLALVGFFMNSFVIGVGQLFRCPTVL---------YWSAVGSG 172

  Fly   177 FINPI--------MPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQ-----------PATDA 222
            .||.:        :|...|...:.|:..||:        .|||.|.:.:           |..::
Mosquito   173 MINYVGNPAEVAAVPHMMLGQRNPMTFFDRV--------ANTLINGVEKILLTYQRYKELPYYES 229

  Fly   223 -LIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVG--PIKPLPQHLLDL 284
             ..||:   |....:|.::|.||:|||.|:..|.||||.||::||||:|:.  | .|:.|.|...
Mosquito   230 NFPAEK---GFRSYDEALRNVSLVLINTHFTQTVPRPYLPNMVEVGGIQINAKP-DPMAQDLQQF 290

  Fly   285 LD-RSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFD 348
            || ...:|.|:||:||.:.|:.|...|..|:...|..||: ..:.:|...|.  ..:|||::...
Mosquito   291 LDGAGRDGAIFISFGSNLRSSNLRQDKLDAILGMIRGLKQ-RVIWKWDQDEM--PNRPSNVFIGK 352

  Fly   349 WLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDF 413
            ||||..:|.||.::.|::||||...:||::.|||::..|.:|||..|...|.:.|:|:.|.|.:.
Mosquito   353 WLPQDAILAHPNLKLFVTHGGLGSISEAMYHGVPIVGIPMFGDQDGNVAQVVKEGWGLSVSFDEL 417

  Fly   414 DSNHITRGL--RIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHIN 476
             :..:..|:  .::.|.|:.|:|:..:..::.||:..::...:|||:||::.||||:..:...:|
Mosquito   418 -TEPLLSGVVQEVLRDPKYREQVQGRALLYKDRPMGALETGVYWIEYVIRHHGAPHLHYQGADLN 481

  Fly   477 WIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            ......:||..|.:|:|:::..|:..:.:..|.|...|..| |.|||.:
Mosquito   482 AFQLALLDVYAFIIGVLYIVYKAVVLIGRKVKRALFGGAKS-DQKTKNK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	149/511 (29%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	135/466 (29%)
AgaP_AGAP007589	XP_001687884.1	egt	20..467	CDD:223071	147/497 (30%)
AgaP_AGAP007589	XP_001687884.1	UDPGT	36..503	CDD:278624	150/517 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020