DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt5c3

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001122186.1	Gene:	ugt5c3 / 563413	ZFINID:	ZDB-GENE-050419-23	Length:	531	Species:	Danio rerio

Alignment Length:	528	Identity:	134/528 - (25%)
Similarity:	253/528 - (47%)	Gaps:	71/528 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISMY----SYFPLEKPVANYTDYV-------FQGM------PLLTD 80
            ||:.....:..||..:||:|.:.    |::..||     :||.       .:||      .:::.
Zfish    38 SHWLNMDILIKALHGKGHSIDVIRNTNSWYVKEK-----SDYYNSITIPQSKGMDEEFVDDMISK 97

  Fly    81 IVDLSNFESEWKPLGLPFKVPTYF--MLHDWGLRS--CKVALNSPLITQLLKS--PIRYDVILLE 139
            :::....:|.|..     .|..:|  ::.::.:..  |.:..:.....::||:  ..:||::|.:
Zfish    98 VINHERGKSSWLS-----TVKLFFDSVIDNYEMTKMVCDITTSIFESEEILKTLQEKQYDLMLTD 157

  Fly   140 HFSNDCMAAV-AHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPY-----TDEMSLIDR 198
            ....  |..: ||.|..|::     ..:.|.....|...|.| .||:::|.     ||.||...|
Zfish   158 PVWG--MGIILAHKLKLPMV-----YNVRWTTTVDGHFNIAP-SPMSYIPITGSGNTDRMSFFQR 214

  Fly   199 LNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPIN--EIVKNTSLMLINQHYALTGPRPYAP 261
            :.|...:.|.:..|:..:.|...|:..:.|.   ||::  ::::...:.|:...:....|||..|
Zfish   215 VKNIIFYFTNDIKYSRFSLPQYQAICDKYFD---PPVDFYQLLQGADIWLMRVDFVFEFPRPTMP 276

  Fly   262 NVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYN 325
            |:|..||.|..|.||||..|.|.:..| .:|||.:|.|:.:::  ||....:.:..:.::|.:
Zfish   277 NIIYTGGFQCTPAKPLPHDLEDFMQSSGDHGVIVMSLGTFISA--LPEDVTAEIAAAFARLPQ-- 337

  Fly   326 FVMRWKSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVT 386
                 |.:.....|:||    |....||:||:|||.|||.:.|::|||..|..||::.|||::..
Zfish   338 -----KVIWRYTGKKPSTLGNNTLLVDWMPQKDLLGHPKTKVFVAHGGTNGVQEALYHGVPVVGI 397

  Fly   387 PFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIK 450
            ||:.||:.|...::.||...||...:...|.:...:: :|.:..:...:::.|:....:|:.|:.
Zfish   398 PFFFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIKEVINNPSYRLTMQKLSQLHLDKPVKPLD 462

  Fly   451 LATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGK 515
            .|.:|||.|:::.||.|:::|:..:.|..|:|:||.:..:.::.:.|.::..:::......|
Zfish   463 SAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVAVTLIAVVLIFIFSIFYVVRYVCIKCC--- 524

  Fly   516 ISRDTKTK 523
             ||..||:
Zfish   525 -SRKRKTE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	128/490 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	117/459 (25%)
ugt5c3	NP_001122186.1	UDPGT	28..530	CDD:278624	132/525 (25%)
ugt5c3	NP_001122186.1	egt	<267..507	CDD:223071	78/248 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584391
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740