DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	540	Identity:	151/540 - (27%)
Similarity:	249/540 - (46%)	Gaps:	62/540 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMY----SYFPLE 61
            |.|:.|.....|..|...:|..|| :|...| ||:.....:...|..|||.:|:.    |:|
Zfish     5 MSLVFLWTSLLLSLPSGYNADKIL-VFPIDG-SHWVNMEVLVKKLQSRGHELSVIRLEDSWF--- 64

  Fly    62 KPVANYTDYVFQGMPLLTDIVDLSNFESEWKP----------LGLPFKVPTYFMLHDWGLRSCKV 116
             ...|...|....:.|....:||..||:..|.          :|:..::..:..:...|..:...
Zfish    65 -IKGNSPYYSSITVTLKKKFIDLDLFETAVKKILDARRDGPIMGVLAQMSEFIGILKVGHGANIA 128

  Fly   117 ALNSPLITQLLKSPIR---YDVILLEHFSNDCM---AAVAHLLNAPVIALSSCAIMPWHYKRMGS 175
            .|.|.|..::|.|.|:   ||::|    ::..|   ..:||.|:.|::     ..:.|.....|.
Zfish   129 MLTSMLENKVLMSQIKMANYDLML----TDPAMPGGVILAHYLHLPMV-----YNVRWMSFGEGH 184

  Fly   176 PFINPIMPMNFLP-----YTDEMSLIDRLNNFFHFHTVNTLYNMITQ-----PATDALIAERFGP 230
            ..|.| .|::|:|     .||.|.|::|..||.|:.     .|:|.:     |...:|:...|.|
Zfish   185 FSIAP-SPISFVPVPGSGLTDRMGLLERSRNFLHYG-----LNLIQERWMVIPMYTSLLLNHFPP 243

  Fly   231 GLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIY 294
            |...:. :.::..|.|:...:....|||..||::.:||.|..|.||||..|.:.:..| .:||:.
Zfish   244 GTDLLT-MQRSAELWLVRADFVFEFPRPSMPNLVYIGGFQCRPAKPLPADLEEFMQSSGDHGVVV 307

  Fly   295 ISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHP 359
            :|.|:::..  ||.....|:..:.:|:.:   .:.|:.:........:|.....||||.|||.||
Zfish   308 MSLGTLIAG--LPKEVMEAIASAFAQIPQ---KVIWRFIGQRPSTLGNNTLLIQWLPQNDLLGHP 367

  Fly   360 KIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRI 424
            |.|||::|||..|..|||:.|||:|..|...||..|...::.||...::|.....:......|..
Zfish   368 KTRAFVAHGGTNGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCSTKEFLVALTD 432

  Fly   425 ILDK-KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLF 488
            ||:. .:.:.:::.|...|.||:.|:..|.:|||.|::..||||:::||.:::...|..:||:..
Zfish   433 ILENPTYRQNMQKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEFSYYCLDVVAL 497

  Fly   489 WLGILFLLIVALRKLIKIFK 508
               :||:|:..|..:..|.|
Zfish   498 ---VLFMLLGTLGGVYTICK 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	140/499 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	124/454 (27%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	148/531 (28%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	143/517 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740